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2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209)

CASRN 1163-19-5 | DTXSID9020376

On this page:

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (25 pp, 232 K) Last Updated: 06/30/2008

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Nervous 7 x 10 -3 Neurobehavioral effects NOAEL : 2.22
mg/kg 		300 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (25 pp, 232 K) Last Updated: 06/30/2008

Information reviewed but value not estimated.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (25 pp, 232 K) Last Updated: 06/30/2008

WOE Characterization Framework for WOE Characterization
Suggestive evidence of carcinogenic potential Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005)
Basis:
  • Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005a), the database for decabromodiphenyl ether provides suggestive evidence of carcinogenic potential.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (25 pp, 232 K)

Oral Slope Factor: 7 x 10-4 per mg/kg-day
Drinking Water Unit Risk: 2 x 10-8 per µg/L
Extrapolation Method: Multistage model with linear extrapolation from the point of departure (LED12).
Tumor site(s): Hepatic
Tumor type(s): Liver neoplastic nodules or carcinoma (combined) (NTP (1986))

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (25 pp, 232 K)

Not Assessed under the IRIS Program.

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:

Related Links

Critical Effects

Nervous
Nervous

Tumor Sites

Hepatic
Hepatic

Chemical Structure

2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209)

Synonyms

  • BDE-209
  • Benzene, 1,1'-oxybis(2,3,4,5,6-pentabromo-
  • DBDPE
  • DBDPO
  • DecaBDE
  • Decabromobiphenyl ether
  • Decabromobiphenyl oxide
  • Decabromodiphenyl ether
  • Decabromodiphenyl oxide
  • Decabromophenyl ether
  • Ether, bis(pentabromophenyl)
  • Ether, decabromodiphenyl
  • Pentabromophenyl ether
  • 1163-19-5
  • 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209)
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