2,4,6-Trichlorophenol
CASRN 88-06-2 | DTXSID5021386
- IRIS Summary (PDF) (13 pp, 115 K)
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 115 K) Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 115 K) Last Updated: 07/01/1991
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(13 pp, 115 K)
Last Updated: 06/01/1990
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Based on no human data and sufficient evidence in animals; namely, increased incidence of lymphomas or leukemias in male rats and hepatocellular adenomas or carcinomas in male and female mice.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 115 K)
Oral Slope Factor:
1.1
x 10-2
per mg/kg-day
Drinking Water Unit Risk:
3.1
x 10-7
per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hematologic
Tumor type(s): Leukemia (NCI, 1979)
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 115 K)
Inhalation Unit Risk:
3.1
x 10-6
per µg/m3
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hematologic
Tumor type(s): Leukemia (NCI, 1979)
Other EPA Information
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Tumor Sites
Chemical Structure
Synonyms
- Dowicide 2s
- NCI-C02904
- Omal
- Phenachlor
- Phenol, 2,4,6-trichloro-
- RCRA Waste Number U231
- Trichlorophenol
- Trichlorophenol, 2,4,6-
- 2,4,6-Trichlorophenol
- 88-06-2