Bis(chloroethyl)ether (BCEE)
CASRN 111-44-4 | DTXSID9020168
- IRIS Summary (PDF) (10 pp, 104 K)
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 104 K) Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 104 K) Last Updated: 10/01/1991
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(10 pp, 104 K)
Last Updated: 03/31/1987
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Positive carcinogenicity results in two strains of mice and evidence of mutagenicity
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 104 K)
Oral Slope Factor:
1.1
per mg/kg-day
Drinking Water Unit Risk:
3.3
x 10-5
per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Hepatomas (Innes et al., 1969)
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 104 K)
Inhalation Unit Risk:
3.3
x 10-4
per µg/m3
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Hepatomas (Innes et al., 1969)
Other EPA Information
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- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Related Links
Tumor Sites
Chemical Structure
Synonyms
- BCEE
- Bis(2-chloroethyl) ether
- Bis(beta-chloroethyl) ether
- Bis(chloroethyl)ether
- Bis(chloroethyl)ether (BCEE)
- Chlorex
- Chloroethyl ether
- Clorex
- DCEE
- Di(2-chloroethyl) ether
- Di(beta-chloroethyl)ether
- Dichloroether
- Dichloroethyl ether
- Dichloroethyl oxide
- Dwuchlorodwuetylowy eter
- ENT 4,504
- Ethane, 1,1'-oxybis(2-chloro-
- Ether dichlore
- Ether, bis(2-chloroethyl)
- Oxyde de chlorethyle
- RCRA Waste Number u025
- UN 1916
- beta,beta'-Dichloroethyl ether
- beta,beta-Dichlorodiethyl ether
- sym-Dichloroethyl ether
- 1,1'-Oxybis(2-chloro)ethane
- 1-Chloro-2-(beta-chloroethoxy)ethane
- 111-44-4
- 2,2'-Dichloorethylether
- 2,2'-Dichlor-diaethylaether
- 2,2'-Dichlorethyl ether
- 2,2'-Dichloroethyl ether
- 2,2'-Dicloroetiletere