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Bromomethane

CASRN 74-83-9 | DTXSID8020832

  • IRIS Summary (PDF) (29 pp, 184 K)

On this page:

  • Key IRIS
    Values
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (29 pp, 184 K) Last Updated: 09/26/1988

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Gastrointestinal 1.4 x 10 -3 Epithelial hyperplasia of the forestomach NOAEL : 1.4
mg/kg-day
1000 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (29 pp, 184 K) Last Updated: 04/01/1992

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous, Respiratory 5 x 10 -3 Degenerative and proliferative lesions of the olfactory epithelium of the nasal cavity LOAEL (HEC): 4.8 x 10-1
mg/m3
100 High

Cancer Assessment

Weight of Evidence for Cancer (PDF) (29 pp, 184 K) Last Updated: 06/01/1989

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Inadequate human and animal data: a single mortality study from which direct exposure associations could not be deduced and studies in several animal species with too few animals, too brief exposure or observation time for adequate power. Bromomethane has shown genotoxicity.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (29 pp, 184 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (29 pp, 184 K)

Not assessed under the IRIS Program.

Chemical Documents

Jun 1987: Health Effects Assessment for Bromomethane (Report)

Jun 1986: Health And Environmental Effects Profile for Methyl Bromide (Report)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • NIH ToxNet Bromomethane Record
  • ATSDR Toxicological Profile for Bromomethane
  • EPA's Office of Air Quality Planning and Standards Hazardous Air Pollutants Fact Sheet
  • EPA Chemicals Dashboard - Bromomethane
  • eChemPortal - Bromomethane

Critical Effects

Gastrointestinal
Gastrointestinal

Nervous
Nervous

Respiratory
Respiratory

Chemical Structure

Bromomethane

Synonyms

  • Brom-o-gas
  • Bromomethane
  • Curafume
  • Dowfume MC-2 Soil Fumigant
  • Dowfume MC-33
  • EDCO
  • Embafume
  • Halon 1001
  • Haltox
  • Iscobrome
  • Kayafume
  • MB
  • MBX
  • MEBR
  • Metafume
  • Methane, bromo-
  • Methogas
  • Methyl bromide
  • Monobromomethane
  • Pestmaster
  • Profume
  • R40B1
  • Rotox
  • Terabol
  • Terr-o-gas 100
  • Zytox
  • 74-83-9
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