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Diethyl phthalate (DEP)

CASRN 84-66-2 | DTXSID7021780

  • IRIS Summary (PDF) (10 pp, 103 K)
  • Status: Development of the diethyl phthalate (dep) (re)assessment has been discontinued .

On this page:

  • Key IRIS
    Values
  • Assessment
    Status
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (10 pp, 103 K) Last Updated: 09/30/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Other 8 x 10 -1 Decreased growth rate, food consumption and altered organ weights NOAEL : 7.50 x 102
mg/kg-day
1000 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (10 pp, 103 K)

Not assessed under the IRIS Program.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (10 pp, 103 K) Last Updated: 09/07/1988

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Pertinent data regarding carcinogenicity were not located in the available literature.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 103 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 103 K)

Not assessed under the IRIS Program.

Program Outlook Details

Public Assessment Materials Date
Preliminary Assessment Materials/Systematic Review Protocol Mar-2014
Discontinued Dec-2018

Note: The diethyl phthalate (dep) (re)assessment has been discontinued. A new/updated assessment will not be added to the IRIS database at this time.

Chemical Documents

Apr 2014: IRIS Toxicological Review of Diethyl Phthalate (DEP) (Preliminary Assessment Materials) (Report)

Dec 2008: Phthalates and Cumulative Risk Assessment (NAS Final Report) (Other)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Diethyl phthalate (DEP)

Chemical Structure

Diethyl phthalate (DEP)

Synonyms

  • Anozol
  • DPX-f5384
  • Diethyl phthalate
  • Estol 1550
  • Ethyl phthalate
  • NCI-C60048
  • Neantine
  • Palatinol A
  • Phthalol
  • Phthalsaeurediaethylester
  • Placidol E
  • RCRA Waste Number u088
  • 1,2-Benzenedicarboxylic acid, diethyl ester
  • 84-66-2
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