Coke oven emissions

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 114 K) Last Updated:

Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 114 K)

Not assessed under the IRIS Program.

Weight of Evidence for Cancer (PDF) (13 pp, 114 K) Last Updated: 05/01/1989

• Studies of coke oven workers have shown increased risk of mortality from cancer of the lung, trachea and bronchus; cancer of the kidney; cancer of the prostate; and cancer at all sites combined. In animals, extracts and condensates of coke oven emissions were found to be carcinogenic in both inhalation studies and skin-painting bioassays. The mutagenicity of whole extracts and condensates, as well as their individual components, provides supportive evidence for carcinogenicity.
• This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 114 K)

Not Assessed under the IRIS Program.

Inhalation Unit Risk: 6.2 x 10^-4 per µg/m³
Extrapolation Method: Linearized multistage procedure
Tumor site(s): Respiratory
Tumor type(s): Respiratory cancer (Mazumdar et al., 1975; Land, 1976)