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Aramite

CASRN 140-57-8 | DTXSID3020097

  • IRIS Summary (PDF) (14 pp, 125 K)

On this page:

  • Key IRIS
    Values
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 125 K) Last Updated:

Not assessed under the IRIS Program.


Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 125 K)

Not assessed under the IRIS Program.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (14 pp, 125 K) Last Updated: 06/01/1991

WOE Characterization Framework for WOE Characterization
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Based on no human data and sufficient data from animal bioassays including increased incidence of liver tumors and/or neoplastic nodules in three strains of male and female rats and males of one strain of mice, and extrahepatic biliary system tumors in dogs following chronic oral exposure.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 125 K)

Oral Slope Factor: 2.5 x 10-2 per mg/kg-day
Drinking Water Unit Risk: 7.1 x 10-7 per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Neoplastic liver nodules and carcinomas (Popper et al., 1960; Oser and Oser, 1962)


Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 125 K)

Inhalation Unit Risk: 7.1 x 10-6 per µg/m3
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Neoplastic liver nodules and carcinomas (Popper et al., 1960; Oser and Oser, 1962)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Aramite
  • eChemPortal - Aramite

Tumor Sites

Hepatic
Hepatic

Chemical Structure

Aramite

Synonyms

  • AI3-16519
  • Acaracide
  • Aracide
  • Aramit
  • Aramite
  • Aramite
  • Aramite-15W
  • Aratron
  • Butylphenoxyisopropyl chloroethyl sulfite
  • CES
  • Caswell No. 131
  • Compound 88R
  • ENT 16,519
  • EPA Pesticide Chemical Code 062501
  • Ethanol, 2-chloro-, 2-(p-t-butylphenoxy)-1-methylethyl sulfite
  • Ethanol, 2-chloro-, ester with 2-(p-tert-butylphenoxy)-1-methylethyl sulfite
  • NSC 404155
  • Niagaramite
  • Ortho-Mite
  • Sulfurous acid, 2-(p-t-butylphenoxy)-1-methylethyl-2-chloroethyl ester
  • Sulfurous acid, 2-(p-t-butylphenoxy)-1-methylethyl-2-chloroethyl ester
  • Sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester
  • Sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl ester
  • Sulfurous acid, 2-chloroethyl 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl ester
  • Sulfurous acid, 2-chloroethyl 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl ester
  • Sulfurous acid, 2-chloroethyl-, 2-(4-(1,1-dimethylethyl)phenoxy)-1-methylethyl ester
  • aramiteararamite-15w
  • beta-Chloroethyl-beta'-(p-t-butylphenoxy)-alpha'-methylethyl sulfite
  • beta-Chloroethyl-beta-(p-t-butylphenoxy)-alpha-methylethyl sulphite
  • 140-57-8
  • 2-(4-t-Butylphenoxy)isopropyl-2-chloroethyl sulfite
  • 2-(4-t-Butylphenoxy)isopropyl-2-chloroethyl sulphite
  • 2-(4-tert-Butylphenoxy)isopropyl 2-chloroethyl sulfite
  • 2-(4-tert-Butylphenoxy)isopropyl-2-chloroethyl sulfite
  • 2-(p-Butylphenoxy)-1-methylethyl 2-chloroethyl sulfite
  • 2-(p-Butylphenoxy)isopropyl 2-chloroethyl sulfite
  • 2-(p-t-Butylphenoxy)-1-methylethyl 2'-chloroethyl sulphite
  • 2-(p-t-Butylphenoxy)-1-methylethyl 2-chloroethyl ester of sulphurous acid
  • 2-(p-t-Butylphenoxy)-1-methylethyl sulphite of 2-chloroethanol
  • 2-(p-t-Butylphenoxy)-1-methylethyl-2-chloroethyl sulfite
  • 2-(p-t-Butylphenoxy)isopropyl 2'-chloroethyl sulfite
  • 2-(p-t-Butylphenoxy)isopropyl 2'-chloroethyl sulphite
  • 2-(p-terc.Butylfenoxy)isopropyl-2'-chlorethylester kyseliny siricite [Czech]
  • 2-(p-tert-Butylphenoxy)-1-methylethyl 2'-chloroethyl sulfite
  • 2-(p-tert-Butylphenoxy)-1-methylethyl 2-chloroethylsulfite
  • 2-(p-tert-Butylphenoxy)-1-methylethyl sulfite of 2-chloroethanol
  • 2-(p-tert-Butylphenoxy)-1-methylethyl-2-choroethyl sulfite
  • 2-(p-tert-Butylphenoxy)isopropyl 2-chloroethyl sulfite
  • 2-Chloroethyl 1-methyl-2-(p-t-butylphenoxy)ethyl sulphate
  • 2-Chloroethyl 1-methyl-2-(p-tert-butylphenoxy)ethyl sulfite
  • 2-Chloroethyl sulfite of 1-(p-t-butylphenoxy)-2-propanol
  • 2-Chloroethyl sulphite of 1-(p-t-butylphenoxy)-2-propanol
  • 2-Propanol, 1-(p-t-butylphenoxy)-, 2-chloroethyl sulfite
  • 2-Propanol, 1-(p-tert-butylphenoxy)-, 2-chloroethyl sulfite
  • 2-p-tert-Butylphenoxyisopropyl 2-chloroethyl sulfite
  • 88-R
  • 88R
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