Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
IRIS
Contact Us

Barium and Compounds

CASRN 7440-39-3 | DTXSID8023894

  • Toxicological Review (PDF) (88 pp, 325 K)
  • IRIS Summary (PDF) (34 pp, 208 K)

On this page:

  • Key IRIS
    Values
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (34 pp, 208 K) Last Updated: 07/11/2005

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Urinary 2 x 10 -1 Nephropathy BMDL 05 : 63
mg/kg-day
300 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (34 pp, 208 K) Last Updated: 03/30/1998

Information reviewed but value not estimated.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (34 pp, 208 K) Last Updated: 03/30/1998

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Carcinogenic potential cannot be determined (Inhalation route) Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996)
Not likely to be carcinogenic to humans (Oral route) Proposed Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1996)
Basis:
  • Under EPA's 1986 Guidelines for Carcinogen Risk Assessment, barium would be classified as Group D, not classifiable as to human carcinogenicity. Under the Proposed Guidelines for Carcinogenic Risk Assessment (U.S. EPA, 1996), barium is considered not likely to be carcinogenic to humans following oral exposure and its carcinogenic potential cannot be determined following inhalation exposure.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (34 pp, 208 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (34 pp, 208 K)

Not assessed under the IRIS Program.

Chemical Documents

Aug 2004: Proposed Oral Reference Dose (RfD) For Barium And Compounds (Final Report, 2004) (Report)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Barium and Compounds
  • eChemPortal - Barium and Compounds

Critical Effects

Urinary
Urinary

Chemical Structure

Barium and Compounds

Synonyms

  • Barium
  • Barium and Compounds
  • UN 1399
  • UN 1400
  • UN 1854
  • 7440-39-3
  • IRIS Home
  • About IRIS
  • IRIS Recent Additions
  • IRIS Calendar
  • IRIS Assessments
  • Advanced Search
  • IRIS Program Materials
Contact Us to ask a question, provide feedback, or report a problem.
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.