Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
IRIS
Contact Us

Cyclohexane

CASRN 110-82-7 | DTXSID4021923

  • Toxicological Review (PDF) (87 pp, 4.8 M)
  • IRIS Summary (PDF) (16 pp, 183 K)

On this page:

  • Key IRIS
    Values
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (16 pp, 183 K) Last Updated: 09/11/2003

Information reviewed but value not estimated.


Reference Concentration for Inhalation Exposure (RfC) (PDF) (16 pp, 183 K) Last Updated: 09/11/2003

System RfC (mg/m3) Basis PoD Composite UF Confidence
Developmental 6 Reduced pup weights in the F1 and F2 generations BMCL 1sd (HEC): 1822
mg/m3
300 Low/Medium

Cancer Assessment

Weight of Evidence for Cancer (PDF) (16 pp, 183 K) Last Updated: 09/11/2003

WOE Characterization Framework for WOE Characterization
Data are inadequate for an assessment of human carcinogenic potential Revised Draft Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1999)
Basis:
  • Cyclohexane is characterized as "Data are inadequate for an assessment of human carcinogenic potential" (U.S. EPA, 1999).
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (16 pp, 183 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (16 pp, 183 K)

Not assessed under the IRIS Program.

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Cyclohexane
  • eChemPortal - Cyclohexane

Critical Effects

Developmental
Developmental

Chemical Structure

Cyclohexane

Synonyms

  • Benzene, hexahydro-cicloesano (Italian)
  • Benzenehexahydride
  • Cyclohexaan (Dutch)
  • Cyclohexan (German)
  • Cykloheksan (Polish)
  • Hexahydrobenzene
  • Hexamethylene
  • Hexanaphthene
  • IRIS Home
  • About IRIS
  • IRIS Recent Additions
  • IRIS Calendar
  • IRIS Assessments
  • Advanced Search
  • IRIS Program Materials
Contact Us to ask a question, provide feedback, or report a problem.
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.