Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
IRIS
Contact Us

Styrene

CASRN 100-42-5 | DTXSID2021284

  • IRIS Summary (PDF) (26 pp, 169 K)

On this page:

  • Key IRIS
    Values
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (26 pp, 169 K) Last Updated: 01/31/1987

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Hepatic, Hematologic 2 x 10 -1 Red blood cell and liver effects NOAEL : 2.00 x 102
mg/kg-day
1000 Medium

Reference Concentration for Inhalation Exposure (RfC) (PDF) (26 pp, 169 K) Last Updated: 11/01/1992

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous 1 CNS effects NOAEL (HEC): 3.4 x 101
mg/m3
30 Medium

Cancer Assessment

Weight of Evidence for Cancer (PDF) (26 pp, 169 K)
Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (26 pp, 169 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (26 pp, 169 K)

Not assessed under the IRIS Program.

Chemical Documents

Jan 1998: IRIS Documentation For Styrene (Other)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Styrene
  • eChemPortal - Styrene

Critical Effects

Hematologic
Hematologic

Hepatic
Hepatic

Nervous
Nervous

Chemical Structure

Styrene

Synonyms

  • Benzene, vinyl-
  • Cinnamene
  • Cinnamenol
  • Cinnamol
  • Diarex hf 77
  • Ethenylbenzene
  • Ethylene, phenyl-
  • NCI-C02200
  • Phenethylene
  • Phenylethene
  • Phenylethylene
  • Stirolo
  • Styreen
  • Styren
  • Styrene
  • Styrene, monomer
  • Styrol
  • Styrole
  • Styrolene
  • Styropol
  • Styropor
  • UN 2055
  • 100-42-5
  • IRIS Home
  • About IRIS
  • IRIS Recent Additions
  • IRIS Calendar
  • IRIS Assessments
  • Advanced Search
  • IRIS Program Materials
Contact Us to ask a question, provide feedback, or report a problem.
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.