Bis(chloroethyl)ether (BCEE)
CASRN 111-44-4 | DTXSID9020168
- IRIS Summary (PDF) (10 pp, 104 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(10 pp, 104 K)
Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(10 pp, 104 K)
Last Updated: 10/01/1991
Information reviewed but value not estimated.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(10 pp, 104 K)
Last Updated: 03/31/1987
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Positive carcinogenicity results in two strains of mice and evidence of mutagenicity
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (10 pp, 104 K)
Oral Slope Factor:
1.1
per mg/kg-day
Drinking Water Unit Risk:
3.3
x 10-5
per µg/L
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Hepatomas (Innes et al., 1969)
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (10 pp, 104 K)
Inhalation Unit Risk:
3.3
x 10-4
per µg/m3
Extrapolation Method: Linearized multistage procedure, extra risk
Tumor site(s): Hepatic
Tumor type(s): Hepatomas (Innes et al., 1969)
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