Bromomethane
CASRN 74-83-9 | DTXSID8020832
- IRIS Summary (PDF) (29 pp, 184 K)
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (29 pp, 184 K) Last Updated: 09/26/1988
System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Gastrointestinal | 1.4 x 10 -3 | Epithelial hyperplasia of the forestomach |
NOAEL
:
1.4
mg/kg-day |
1000 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF) (29 pp, 184 K) Last Updated: 04/01/1992
System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Nervous, Respiratory | 5 x 10 -3 | Degenerative and proliferative lesions of the olfactory epithelium of the nasal cavity |
LOAEL
(HEC):
4.8
x 10-1 mg/m3 |
100 | High |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(29 pp, 184 K)
Last Updated: 06/01/1989
WOE Characterization | Framework for WOE Characterization |
---|---|
D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Inadequate human and animal data: a single mortality study from which direct exposure associations could not be deduced and studies in several animal species with too few animals, too brief exposure or observation time for adequate power. Bromomethane has shown genotoxicity.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (29 pp, 184 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (29 pp, 184 K)
Not assessed under the IRIS Program.
Chemical Documents
Other EPA Information
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Related Links
Critical Effects
Chemical Structure
Synonyms
- Brom-o-gas
- Bromomethane
- Curafume
- Dowfume MC-2 Soil Fumigant
- Dowfume MC-33
- EDCO
- Embafume
- Halon 1001
- Haltox
- Iscobrome
- Kayafume
- MB
- MBX
- MEBR
- Metafume
- Methane, bromo-
- Methogas
- Methyl bromide
- Monobromomethane
- Pestmaster
- Profume
- R40B1
- Rotox
- Terabol
- Terr-o-gas 100
- Zytox
- 74-83-9