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Acetaldehyde

CASRN 75-07-0 | DTXSID5039224

  • IRIS Summary (PDF) (20 pp, 147 K)

On this page:

  • Key IRIS
    Values
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (20 pp, 147 K) Last Updated:

Not assessed under the IRIS Program.


Reference Concentration for Inhalation Exposure (RfC) (PDF) (20 pp, 147 K) Last Updated: 10/01/1991

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous, Respiratory 9 x 10 -3 Degeneration of olfactory epithelium NOAEL (HEC): 8.7
mg/m3
1000 Low

Cancer Assessment

Weight of Evidence for Cancer (PDF) (20 pp, 147 K) Last Updated: 06/30/1988

WOE Characterization Framework for WOE Characterization
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Based on increased incidence of nasal tumors in male and female rats and laryngeal tumors in male and female hamsters after inhalation exposure.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (20 pp, 147 K)

Not Assessed under the IRIS Program.


Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (20 pp, 147 K)

Inhalation Unit Risk: 2.2 x 10-6 per µg/m3
Extrapolation Method: Linearized multistage-variable exposure input form (extra risk)
Tumor site(s): Respiratory
Tumor type(s): Nasal squamous cell carcinoma or adenocarcinoma (Woutersen and Appleman, 1984)

Chemical Documents

Feb 2003: IRIS Toxicological Review and Risk Characterization of Formaldehyde/Vinyl Acetate/Acetaldehyde: Based on Mode of Action (Other)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Acetaldehyde
  • eChemPortal - Acetaldehyde

Critical Effects

Nervous
Nervous

Respiratory
Respiratory

Tumor Sites

Respiratory
Respiratory

Chemical Structure

Acetaldehyde

Synonyms

  • Acetaldehyd
  • Acetaldehyde
  • Acetic aldehyde
  • Acetylaldehyde
  • Aldehyde acetique
  • Aldeide acetica
  • Ethanal
  • Ethyl aldehyde
  • NCI-C56326
  • Octowy aldehyd
  • RCRA Waste Number u001
  • UN 1089
  • 75-07-0
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