Aldicarb
CASRN 116-06-3 | DTXSID0039223
- IRIS Summary (PDF) (24 pp, 161 K)
- Status: EPA announced in a 2004 Federal Register Notice that chemicals used as pesticides would not be re-assessed by the IRIS Program. This entry in the IRIS database is preserved at the request of EPA program and regional offices. Additional toxicological information may be found under "Other EPA Information."
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (24 pp, 161 K) Last Updated: 11/01/1993
System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Nervous | 1 x 10 -3 | Sweating as clinical sign of AChe inhibition |
NOAEL
:
1
x 10-2
mg/kg-day |
10 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF) (24 pp, 161 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(24 pp, 161 K)
Last Updated: 08/22/1988
WOE Characterization | Framework for WOE Characterization |
---|---|
D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Aldicarb was not found to induce statistically significant increases in tumor incidence in mice or rats in feeding studies or mice in a skin painting study. In the feeding studies there were, however, significant trends in pituitary tumors in female rats and fibrosarcomas in the male mouse. This evidence, together with the fact that less than maximum tolerated doses were used, indicates that the available assays are inadequate to assess the carcinogenic potential of aldicarb.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (24 pp, 161 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (24 pp, 161 K)
Not assessed under the IRIS Program.
Other EPA Information
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Related Links
Critical Effects
Chemical Structure
Synonyms
- Aldecarb
- Aldicarb
- Ambush
- Carbamyl
- Carbanolate
- ENT 27,093
- NCI-c08640
- OMS 771
- Propanal, 2-methyl-2-(methylthio)-, o-((methylamino)carbonyl)oxime
- Propionaldehyde, 2-methyl-2-(methylthio)-, o-(methyl-carbamoyl)oxime
- Sulfone aldoxycarb
- Temic
- Temik
- Temik 10 g
- Temik TSK
- Temik g 10
- UC 21149
- Union Carbide 21149
- Union Carbide UC-21149
- 116-06-3
- 2-Methyl-2-(methylthio)propanal, o-((methylamino)carbonyl) oxime
- 2-Methyl-2-(methylthio)propionaldehyde o-(methylcarbamoyl)oxime