Methanol
CASRN 67-56-1 | DTXSID2021731
- Toxicological Review (PDF) (212 pp, 3.46 M)
- IRIS Summary (PDF) (6 pp, 86 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(6 pp, 86 K)
Last Updated: 09/30/2013
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Developmental | 2 | Extra cervical ribs |
BMDL
05
(internal):
43.1
mg/L |
100 | Medium/High |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(6 pp, 86 K)
Last Updated: 09/30/2013
| System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous, Developmental | 2 x 10 1 | Reduced brain weight in rat pups at 6 weeks of age |
BMDL
1SD
(internal):
858
mg-hr/L |
100 | Medium/High |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(6 pp, 86 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (6 pp, 86 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (6 pp, 86 K)
Not assessed under the IRIS Program.
Sep 2013: IRIS Toxicological Review of Methanol (Noncancer) (Final Report) (Report)
Sep 2013: IRIS Toxicological Review of Methanol (Noncancer) (Interagency Science Discussion Draft) (Report)
Nov 2012: IRIS Toxicological Review of Methanol (Noncancer) (Revised External Review Draft) (Report)
Nov 2011: IRIS Toxicological Review of Methanol (Non-Cancer) (External Review Draft; April 2011) (Report)
Nov 2009: IRIS Toxicological Review of Methanol (Interagency Science Consultation Draft) (Report)
Sep 2009: IRIS Toxicological Review of Methanol (External Review Draft; December 2009) (Report)
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
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