IRIS

Mercury, elemental

CASRN 7439-97-6 | DTXSID1024172

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (28 pp, 177 K) Last Updated:
Not assessed under the IRIS Program.

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (28 pp, 177 K) Last Updated: 06/01/1995

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous 3 x 10 -4 Hand tremor; increases in memory disturbances; slight subjective and objective evidence of autonomic dysfunction LOAEL (ADJ): 9 x 10-3
mg/m3
30 Medium

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (28 pp, 177 K) Last Updated: 05/01/1995

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Based on inadequate human and animal data. Epidemiologic studies failed to show a correlation between exposure to elemental mercury vapor and carcinogenicity; the findings in these studies were confounded by possible or known concurrent exposures to other chemicals, including human carcinogens, as well as lifestyle factors (e.g., smoking). Findings from genotoxicity tests are severely limited and provide equivocal evidence that mercury adversely affects the number or structure of chromosomes in human somatic cells.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (28 pp, 177 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (28 pp, 177 K)

Not assessed under the IRIS Program.


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