Manganese
CASRN 7439-96-5 | DTXSID2024169
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(48 pp, 265 K)
Last Updated: 11/01/1995
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous | 1.4 x 10 -1 | CNS effects |
NOAEL
:
1.4
x 10-1 mg/kg-day |
1 | Medium |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(48 pp, 265 K)
Last Updated: 12/01/1993
| System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Nervous | 5 x 10 -5 | Impairment of neurobehavioral function |
LOAEL
(HEC):
5
x 10-2 mg/m3 |
1000 | Medium |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(48 pp, 265 K)
Last Updated: 09/26/1988
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Existing studies are inadequate to assess the carcinogenicity of manganese.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (48 pp, 265 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (48 pp, 265 K)
Not assessed under the IRIS Program.
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