Dibutyl phthalate (DBP)

CASRN 84-74-2 | DTXSID2021781

IRIS Summary (PDF) (11 pp, 107 K)
Status: Development of the dibutyl phthalate (dbp) (re)assessment has been discontinued .

On this page:

Key IRIS
Values
Assessment
Status
Chemical
Documents
Other EPA
Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (11 pp, 107 K) Last Updated: 01/31/1987

System	RfD (mg/kg-day)	Basis	PoD	Composite UF	Confidence
Other	1 x 10 ^-1	Increased mortality	NOAEL : 1.25 x 10² mg/kg-day	1000	Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (11 pp, 107 K) Last Updated: 10/01/1990

Information reviewed but value not estimated.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (11 pp, 107 K) Last Updated: 09/07/1988

WOE Characterization	Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity)	Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)

Basis:

Pertinent data regarding carcinogenicity was not located in the available literature.
This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (11 pp, 107 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (11 pp, 107 K)

Not assessed under the IRIS Program.

Program Outlook Details

Public Assessment Materials	Date
Preliminary Assessment Materials/Systematic Review Protocol	Jan-2015
Discontinued	Dec-2018

Note: The dibutyl phthalate (dbp) (re)assessment has been discontinued. A new/updated assessment will not be added to the IRIS database at this time.

Chemical Documents

Jan 2015: IRIS Toxicological Review of Dibutyl Phthalate (Dbp) (Preliminary Assessment Materials) (Report)

Nov 2012: An Approach for Integrating Toxicogenomic Data in Risk Assessment: The Dibutyl Phthalate Case Study (Journal)

Dec 2008: Phthalates and Cumulative Risk Assessment (NAS Final Report) (Other)

Aug 2006: EPA Peer Consultation Workshop Report on the Review of the Draft IRIS Toxicological Review of Dibutyl Phthalate (DBP) (Other)

Jun 2006: IRIS Toxicological Review of Dibutyl Phthalate (DBP) (External Review Draft) 2006 (Report)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:

Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.