Allyl chloride
CASRN 107-05-1 | DTXSID4039231
- IRIS Summary (PDF) (13 pp, 139 K)
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 139 K) Last Updated:
Not assessed under the IRIS Program.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 139 K) Last Updated: 12/01/1991
System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Nervous | 1 x 10 -3 | Functional and histological peripheral neurotoxicity |
NOAEL
(HEC):
3.6
mg/m3 |
3000 | Low |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(13 pp, 139 K)
Last Updated: 09/01/1990
WOE Characterization | Framework for WOE Characterization |
---|---|
C (Possible human carcinogen) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Classification is based on a low (but biologically important) incidence of forestomach tumors in female mice and positive results in a variety of genetic toxicity tests. Allyl chloride is an alkylating agent and structurally related to probable human carcinogens.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 139 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 139 K)
Not assessed under the IRIS Program.
Other EPA Information
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Critical Effects
Chemical Structure
Synonyms
- Allile (cloruro di) [Italian]
- Allyl chloride
- Allylchlorid [German]
- Allyle (chlorure d') [French]
- Chlorallylene
- Chlorure d'allyle [French]
- Cloruro de alilo [Spanish]
- HSDB 178
- NCI-C04615
- NSC 20939
- Propene, 3-chloro-
- UN 1100
- alpha-Chloropropylene
- p-aminopropiofenon [Czech]
- 1-Chloro propene-2
- 1-Chloro-2-propene
- 1-Propene, 3-chloro-
- 107-05-1
- 2-Propenyl chloride
- 3-Chloro-1-propene
- 3-Chloroprene
- 3-Chloropropene
- 3-Chloropropene-1
- 3-Chloropropylene
- 3-Chlorpropen [German]