Pyrene
CASRN 129-00-0 | DTXSID3024289
- IRIS Summary (PDF) (13 pp, 119 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(13 pp, 119 K)
Last Updated: 09/01/1990
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Urinary | 3 x 10 -2 | Kidney effects (renal tubular pathology, decreased kidney weights) |
NOAEL
:
7.5
x 101 mg/kg-day |
3000 | Low |
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(13 pp, 119 K)
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(13 pp, 119 K)
Last Updated: 09/01/1990
| WOE Characterization | Framework for WOE Characterization |
|---|---|
| D (Not classifiable as to human carcinogenicity) | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986) |
- Based on no human data and inadequate data from animal bioassays.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 119 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 119 K)
Not assessed under the IRIS Program.
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