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Pyrene

CASRN 129-00-0 | DTXSID3024289

  • IRIS Summary (PDF) (13 pp, 119 K)

On this page:

  • Key IRIS
    Values
  • Chemical
    Documents
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (13 pp, 119 K) Last Updated: 09/01/1990

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Urinary 3 x 10 -2 Kidney effects (renal tubular pathology, decreased kidney weights) NOAEL : 7.5 x 101
mg/kg-day
3000 Low

Reference Concentration for Inhalation Exposure (RfC) (PDF) (13 pp, 119 K)

Not assessed under the IRIS Program.

Cancer Assessment

Weight of Evidence for Cancer (PDF) (13 pp, 119 K) Last Updated: 09/01/1990

WOE Characterization Framework for WOE Characterization
D (Not classifiable as to human carcinogenicity) Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986)
Basis:
  • Based on no human data and inadequate data from animal bioassays.
  • This may be a synopsis of the full weight-of-evidence narrative.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (13 pp, 119 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (13 pp, 119 K)

Not assessed under the IRIS Program.

Chemical Documents

Jul 1987: HEALTH AND ENVIRONMENTAL EFFECTS PROFILE FOR PYRENE (Report)

Sep 1984: Health Effects Assessment for Pyrene (Report)

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Pyrene
  • eChemPortal - Pyrene

Critical Effects

Urinary
Urinary

Chemical Structure

Pyrene

Synonyms

  • Benzo(def)phenanthrene
  • Beta-pyrene
  • HSDB 4023
  • NSC 17534
  • Pyren [German]
  • Pyrene
  • 129-00-0
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