Phosgene
CASRN 75-44-5 | DTXSID0024260
- Toxicological Review (PDF) (102 pp, 614 K)
- IRIS Summary (PDF) (22 pp, 166 K)
On this page:
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF) (22 pp, 166 K) Last Updated: 01/31/2006
Information reviewed but value not estimated.
Reference Concentration for Inhalation Exposure (RfC) (PDF) (22 pp, 166 K) Last Updated: 01/31/2006
System | RfC (mg/m3) | Basis | PoD | Composite UF | Confidence |
---|---|---|---|---|---|
Respiratory | 3 x 10 -4 | Collagen staining indicative of fibrosis |
BMDL
10
(HEC):
3
x 10-2 mg/m3 |
100 | Medium |
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(22 pp, 166 K)
Last Updated: 01/31/2006
WOE Characterization | Framework for WOE Characterization |
---|---|
Inadequate information to assess carcinogenic potential | Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005) |
- Under the Guidelines for Carcinogen Risk Assessment (U.S. EPA, 2005b), there is inadequate information to assess carcinogenic potential of phosgene. A single epidemiology study was not considered adequate for evaluating carcinogenic potential in humans, and no animal cancer bioassays of phosgene have been conducted.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (22 pp, 166 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (22 pp, 166 K)
Not assessed under the IRIS Program.
Chemical Documents
Other EPA Information
- Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
- Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
- Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.
Related Links
Critical Effects
Chemical Structure
Synonyms
- CG
- Carbon Dichloride Oxide
- Carbon oxychloride
- Carbone (oxychlorure de) [French]
- Carbonic dichloride
- Carbonio (ossicloruro di) [Italian]
- Carbonyl chloride
- Carbonyl dichloride
- Carbonylchlorid [German]
- Chloroformyl chloride
- Fosgeen [Dutch]
- Fosgen [Polish]
- Fosgene [Italian]
- Fosgeno [Spanish]
- HSDB 796
- Koolstofoxychloride [Dutch]
- NCI-C60219
- Phosgen [German]
- Phosgene
- RCRA Waste Number P095
- 75-44-5