IRIS
Contact Us

1,6-Hexamethylene diisocyanate

CASRN 822-06-0 | DTXSID4024143

On this page:

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 126 K) Last Updated:

Not assessed under the IRIS Program.

Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 126 K) Last Updated: 09/01/1994

System RfC (mg/m3) Basis PoD Composite UF Confidence
Nervous, Respiratory 1 x 10 -5 Degeneration of olfactory epithelium NOAEL (HEC): 1 x 10-3
mg/m3 		100 Medium

Cancer Assessment

Weight of Evidence for Cancer (PDF) (14 pp, 126 K)
Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 126 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 126 K)

Not assessed under the IRIS Program.

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:

Related Links

Critical Effects

Nervous
Nervous

Respiratory
Respiratory

Chemical Structure

1,6-Hexamethylene diisocyanate

Synonyms

  • AI3-28285
  • Diisocyanate d'hexamethylene [French]
  • HDI
  • HMDI
  • HSDB 6134
  • Hexamethylendiisokyanat [Czech]
  • Hexamethylene diisocyanate
  • Hexamethylene diisocyanate
  • Hexamethylenediisocyanate
  • Hexametilendilsocianato [Spanish]
  • Hexane 1,6-diisocyanate
  • Hexane, 1,6-diisocyanato-
  • Isocyanic acid, diester with 1,6-hexanediol
  • Isocyanic acid, hexamethylene ester
  • Metyleno-bis-fenyloizocyjanian [Polish]
  • Szesciometylenodwuizocyjanian [polish]
  • TL 78
  • 1,6-Diisocyanatohexane
  • 1,6-Hexamethylene diisocyanate
  • 1,6-Hexanediol diisocyanate
  • 1,6-Hexylene diisocyanate
  • 822-06-0
Contact Us to ask a question, provide feedback, or report a problem.