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Chlorodifluoromethane

CASRN 75-45-6 | DTXSID6020301

  • IRIS Summary (PDF) (12 pp, 119 K)

On this page:

  • Key IRIS
    Values
  • Other EPA
    Information

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 119 K) Last Updated:

Not assessed under the IRIS Program.


Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 119 K) Last Updated: 11/01/1993

System RfC (mg/m3) Basis PoD Composite UF Confidence
Endocrine, Urinary 5 x 10 1 Increased kidney, adrenal and pituitary weights NOAEL (HEC): 5.260 x 103
mg/m3
100 Medium

Cancer Assessment

Weight of Evidence for Cancer (PDF) (12 pp, 119 K)
Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 119 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (12 pp, 119 K)

Not assessed under the IRIS Program.

Other EPA Information

Additional EPA toxicity information may be available by visiting the following sites:
  • Human Health Benchmarks for Pesticides (HHBP). This database provides human health benchmarks for pesticides that may be present in drinking water.
  • Office of Pesticide Programs Pesticide Chemical Search. This database provides links to health effects information and registration status for pesticides.
  • Chemistry Dashboard. This database provides information on chemical structures, experimental and predicted physicochemical, and toxicity data.

Related Links

  • EPA Chemicals Dashboard - Chlorodifluoromethane
  • eChemPortal - Chlorodifluoromethane

Critical Effects

Endocrine
Endocrine

Urinary
Urinary

Chemical Structure

Chlorodifluoromethane

Synonyms

  • Algeon 22
  • Algofrene Type 6
  • Arcton 4
  • CCRIS 858
  • Chlorodifluoromethane
  • Chlorodifluoromethane
  • Chlorofluorocarbon 22
  • Clorodifluometano [Spanish]
  • Difluorochloromethane
  • Difluoromonochloromethane
  • Electro-CF 22
  • Eskimon 22
  • F 22
  • FC 22
  • FC22
  • Fluorocarbon 22
  • Fluorocarbon-22
  • Freon
  • Freon 22
  • Frigen
  • Frigen 22
  • Genetron 22
  • HCFC-22
  • HSDB 143
  • Hydrochlorofluorocarbon 22
  • Isceon 22
  • Isotron 22
  • Khladon 22
  • Methane, chlorodifluoro-
  • Monochlorodifluormethane
  • Monochlorodifluoromethane
  • Propellant 22
  • R 22
  • Refrigerant 22
  • UCON 22
  • 75-45-6
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