Perfluorodecanoic Acid (PFDA)
CASRN 335-76-2 | DTXSID3031860
- IRIS Executive Summary (PDF) (7 pp, 403 K)
Noncancer Assessment
Reference Dose for Oral Exposure (RfD) (PDF)
(7 pp, 403 K)
Last Updated: 07/15/2024
| System | RfD (mg/kg-day) | Basis | PoD | Composite UF | Confidence |
|---|---|---|---|---|---|
| Developmental, Immune | 2 x 10 -9
(Chronic) |
Decreased serum antibody concentrations for tetanus and diphtheria in children; Decreased birth weight in male and female children | 30 | Medium | |
| Developmental, Immune | 2 x 10 -9
(Subchronic) |
Decreased serum antibody concentrations for tetanus and diphtheria in children; Decreased birth weight in male and female children | 30 | Medium |
Note: The chronic and sub-chronic RfDs are based on two similar PODs of 5.44 x 10-8 mg/kg-day (developmental) and 6.04 x 10-8 mg/kg-day (immune). See IRIS toxicological review for more information.
Reference Concentration for Inhalation Exposure (RfC) (PDF)
(7 pp, 403 K)
Last Updated: 07/15/2024
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF)
(7 pp, 403 K)
Last Updated: 07/15/2024
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (7 pp, 403 K)
Not assessed under the IRIS Program.
Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (7 pp, 403 K)
Not assessed under the IRIS Program.
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