IRIS

Perfluorodecanoic Acid (PFDA)

CASRN 335-76-2 | DTXSID3031860

Noncancer Assessment

Reference Dose for Oral Exposure (RfD) (PDF) (7 pp, 403 K) Last Updated: 07/15/2024

System RfD (mg/kg-day) Basis PoD Composite UF Confidence
Developmental, Immune 2 x 10 -9
(Chronic)
Decreased serum antibody concentrations for tetanus and diphtheria in children; Decreased birth weight in male and female children 30 Medium
Developmental, Immune 2 x 10 -9
(Subchronic)
Decreased serum antibody concentrations for tetanus and diphtheria in children; Decreased birth weight in male and female children 30 Medium


Note: The chronic and sub-chronic RfDs are based on two similar PODs of 5.44 x 10-8 mg/kg-day (developmental) and 6.04 x 10-8 mg/kg-day (immune). See IRIS toxicological review for more information.

 


Reference Concentration for Inhalation Exposure (RfC) (PDF) (7 pp, 403 K) Last Updated: 07/15/2024
Not assessed under the IRIS Program.

 

Cancer Assessment

Weight of Evidence for Cancer (PDF) (7 pp, 403 K) Last Updated: 07/15/2024
Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (7 pp, 403 K)

Not assessed under the IRIS Program.

Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (7 pp, 403 K)

Not assessed under the IRIS Program.

Additional EPA toxicity information may be available by visiting the following sites:

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