Pentachlorophenol

Overview

EPA is releasing the draft report, Toxicological Review of Pentachlorophenol, that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments.

Background

The draft Toxicological Review of Pentachlorophenol provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to pentachlorophenol. Pentachlorophenol is a wood preservative used to prevent decay from fungal organisms and insect damage. Use by the public was restricted in 1984, and application was limited to industrial areas. It has been reported in food, surface water, groundwater, rainwater, and soil. People who work or reside in close proximity to wood treatment facilities, treated lumber, or hazardous waste sites are likely exposed.

History/Chronology

Date	Description
May 2009	EPA released the external review draft report for public review and comment.
Jun 2009	EPA announced a public listening session for the draft review report. [Fedral Register Notice Jun 9, 2009]
Jun 2009	EPA announced the external peer review meeting to be held August 4, 2009 in Arlington, VA. [Federal Register Notice Jun 29, 2009]
Oct 2009	EPA released the comments from the external review workshop and public comment period.
Jul 2010	EPA hosted an interagency science discussion on the review of the draft Toxicological Review of Pentachlorophenol .
Sep 2010	EPA releases the final report and the interagency science discussion review draft with comments.

Status

This assessment has been loaded into the IRIS Web site and Database.

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

• IRIS Toxicological Review of Pentachlorophenol (Interagency Science Discussion Draft) (PDF)  (275  pp, 2.0 MB, about PDF)
• Pentachlorophenol Summary (Interagency Science Discussion Draft) (PDF)  (23  pp, 139.6 KB, about PDF)
• 1. ATSDR Pentachlorophenol IASD Comments (PDF)  (3  pp, 61.5 KB, about PDF)
• 2. CEQ Pentachlorophenol IASD Comments (PDF)  (1  pp, 45.9 KB, about PDF)
• 3. OMB Pentachlorophenol IASD Comments (PDF)  (3  pp, 29.3 KB, about PDF)

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Document Related Link(s)

• IRIS Toxicological Review of Pentachlorophenol (External Review Draft)
• IRIS Toxicological Review of Pentachlorophenol (Final Report)