Diisononyl phthalate (DINP)
CASRN 28553-12-0 | DTXSID4022521
IRIS Toxicological Review of Diisononyl Phthalate (Dinp) (Preliminary Assessment Materials)
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Overview
- Draft literature search strategies
- The approach for identifying studies
- The screening process for selecting pertinent studies
- The resulting list of pertinent studies
- Preliminary evidence tables
- The process for selecting studies to include in evidence tables
- The quality of the studies in the evidence tables
Citation
Background
The use of di-2-ethylhexyl phthalate (DEHP) has largely been replaced by DINP, though not in medical products. In 2008, the Consumer Product Safety Improvement Act (CPSIA) placed an interim ban on DINP in children’s toys and certain child care articles at concentrations greater than 0.1 percent. The Chronic Hazard Advisory Panel (CHAP) recommended that the interim ban on DINP be made permanent in children’s toys and child care products at level greater than 0.1%.
History/Chronology
| Date | Description |
|---|---|
| Aug 2014 | EPA released Preliminary Assessment Materials (draft literature searches and associated search strategies, evidence tables and exposure response arrays) in anticipation for discussion at an upcoming IRIS Public Science Meeting. |
| Oct 2014 | EPA discussed DINP at the October 2014 IRIS public science meeting. |
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- Scoping information, preliminary literature search, associated strategy and evidence tables for DINP (PDF) (131 pp, 1.7 MB, about PDF)
- Primary literature search references sorted by author (DINP)
- Literature selection process for the DINP primary literature (dynamic literature link - generated by HERO, leaving the IRIS website)
- Targeted literature search for epidemiological references sorted by author (DINP) (dynamic literature link - generated by HERO)
- Literature selection process for the DINP targeted epidemiological literature (dynamic literature link - generated by HERO)
- IRIS October 2014 Meeting & Presentations
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Chemical Structure for
Diisononyl phthalate (DINP)
