Polychlorinated Biphenyls (PCBs)

CASRN 1336-36-3 | DTXSID5024267

IRIS Toxicological Review of Polychlorinated Biphenyls (PCBs) (Scoping and Problem Formulation Materials)

On this page:

Notice - This site contains archived material(s)

Archive disclaimer
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the Risk Webmaster for assistance. Please use the contact us form if you need additional support.


In March 2015, EPA invited the public to provide input and participate in discussions about problem formulation, preliminary assessment materials, and draft IRIS assessments. During problem formulation, the IRIS Program was looking for input from the scientific community and the general public as it frames the specific scientific issues that were the focus of the systematic review of potential health hazards of PCBs (effects other than cancer).

In October 2014, EPA’s IRIS Program announced an agreement with the National Academies’ National Research Council (NRC) to arrange for independent experts to attend IRIS public science meetings to provide input on the science underlying the development of IRIS assessments. The NRC then selected a limited number of experts to join in the discussion of the key science topics with EPA with those that were registered as discussants on the EPA website. Participation of these experts was meant to be supplementary and stakeholders and the public continued to register as discussants on the EPA website and were also invited to suggest additional science topics prior to the agenda being finalized and released.


U.S. EPA. IRIS Toxicological Review of Polychlorinated Biphenyls (PCBs) (Scoping and Problem Formulation Materials). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/198, 2015.

Top of Page


This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.

Top of Page

Quick Check

Quick check is a visual indication of the current step that this IRIS assessment has started or is in.