Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
IRIS
Contact Us

Arsenic, Inorganic

CASRN 7440-38-2 | DTXSID4023886

  • Toxicological Review (PDF)  (318  pp, 17.0 MB, about PDF)
  • IRIS Summary (PDF)  (6  pp, 422.9 KB, about PDF)
  • Workshop & meeting details from the development of the draft IRIS Assessment for inorganic arsenic
  • Key IRIS
    Values
  • Chemical
    Documents
  • Report
    Details
  • Other EPA
    Information

Inorganic Arsenic Workshop (Jan 2013)

On this page:

  • Meeting Agenda
  • Meeting Materials

Meeting Agenda

EPA is currently revising its Integrated Risk Information System (IRIS) assessment of inorganic arsenic. This assessment addresses both noncancer and cancer human health effects that may result from chronic inhalation exposure to this chemical. To facilitate discussion of several scientific issues pertinent to the assessment, EPA hosted a state-of-the-science workshop. This workshop was open to the public, broadcast by webinar/teleconference, and took place in Arlington, VA on January 8-9, 2013.

Background

EPA is developing a plan for drafting a new IRIS Toxicological Review of Inorganic Arsenic. The first planning step is determining the scope of the Toxicological Review. The scope transparently communicates why the Toxicological Review is being performed and what it will include or exclude. The meeting consisted of 5 sessions of panel discussions focused on a series of charge questions. Lead discussants briefly summarized the available data to address the questions and facilitate discussion with other panelists. Once the panel discussion is over, participants attending the meeting in person or remotely via webinar/teleconference were given the opportunity to ask questions or provide comments within the time constraints of the meeting. In addition to discussions after the panel sessions, time was allotted for participants attending the meeting in person or remotely via webinar/teleconference to provide additional comments.

Meeting Objective

This workshop is designed to inform the development of EPA’s draft Toxicological Review of inorganic arsenic (iAs) (cancer and non-cancer effects), which EPA intends to post to the Integrated Risk Information System (IRIS) database. Workshop participants will be asked to highlight significant new and emerging research that could inform the development of the draft Toxicological Review, discuss methods for identifying the relevant literature, identify major areas of scientific controversy, identify data gaps, and discuss potential approaches for characterizing dose-response.

Workshop Goals:
  • Ensure that EPA provides the public an opportunity to inform the Toxicological Review.
  • Transparently communicate how EPA will produce a Toxicological Review that meets the needs of the Agency and the public.

Workshop participants are encouraged to think broadly about the body of iAs scientific evidence and how it can best be used in a draft Toxicological Review. Attendees are invited to participate in an open dialogue regarding ways in which the data would most effectively be used in the Toxicological Review that will serve as part of the scientific and technical foundations for the Agency’s decisions on iAs. Specifically, workshop discussions will provide important input as EPA considers the design, scope, and methods used to develop the draft Toxicological Review. The Toxicological Review, in turn, will inform risk management decisions by Agency stakeholders and partners. Panelists participating in the workshop represent a range of scientific expertise (e.g., epidemiology, human and animal toxicology, systematic review, risk assessment, dose-response, and mode of action).

Outcome

The outcome of the workshop will inform EPA’s planning for the Toxicological Review and an upcoming National Academy of Sciences (NAS) public workshop on iAs. Development of the draft Toxicological Review will be informed by the key issues and recommendations from the public NAS and EPA meetings. In addition to conducting a workshop, the NAS will also conduct a review of the draft Toxicological Review. Throughout the process, the public is encouraged to take advantage of the opportunities to review and comment on the draft Toxicological Review. The draft Toxicological Review will be revised in response to the NAS and public review comments. The Toxicological Review will be finalized as expeditiously as possible after the NAS review.

Final Reports: EPA produced a planning and scoping summary document at the end of this public workshop. This planning and scoping summary document aims to communicate how EPA will produce the assessment while meeting the needs of the Agency and the American people.

Meeting Materials

  • Inorganic Arsenic Workshop Agenda (PDF)  (8  pp, 190.4 KB, about PDF)
  • Introduction Slides (PDF)  (22  pp, 709.0 KB, about PDF)
  • Session 1 Slides (PDF)  (30  pp, 1.7 MB, about PDF)
  • Session 2 Slides (PDF)  (33  pp, 4.2 MB, about PDF)
  • Session 3 Slides (PDF)  (54  pp, 2.9 MB, about PDF)
  • Session 4 Slides (PDF)  (28  pp, 2.0 MB, about PDF)

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.

Meeting Related Link(s)

  • Arsenic Workshop 2013 - Agenda, Slides and Summary Report (Zip file of materials) (ZIP)  (8.4 MB, about ZIP)
  • Additional Workshop and Meetings from the Development of the Draft IRIS Assessment for inorganic Arsenic

Related Links

  • EPA Chemicals Dashboard - Arsenic, Inorganic
  • Workshop and Meetings from the Development of the Draft IRIS Assessment for inorganic Arsenic
  • eChemPortal - Arsenic, Inorganic

Critical Effect Systems

Cardiovascular
Cardiovascular

Endocrine
Endocrine

Tumor Sites

Respiratory
Respiratory

Urinary
Urinary

Chemical Structure for
Arsenic, Inorganic

Arsenic, Inorganic

Synonyms

  • Arsenic
  • Arsenic, inorganic
  • Arsenic, inorganic
  • Gray-arsenic
  • 7440-38-2
  • IRIS Home
  • About IRIS
  • IRIS Recent Additions
  • IRIS Calendar
  • IRIS Assessments
  • Advanced Search
  • IRIS Program Materials
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on August 17, 2022
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.