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Vanadium and Compounds (Inhalation)

CASRN Various

  • Status: vanadium and compounds (inhalation) is in step 1 at this time.
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IRIS Assessment Plan for Inhalation Exposure to Vanadium and Compounds (Scoping and Problem Formulation Materials)

On this page:

  • Overview
  • Background
  • Downloads

Alert
Alert Notice - This site contains archived material(s)

Archive disclaimer
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the IRIS Webmaster for assistance. Please use the contact us form if you need additional support.

Overview

In May 2021, EPA released the draft IRIS Assessment Plan (IAP) for Inhalation Exposure to Vanadium and Compounds for public review and comment. An IRIS Assessment Plan (IAP) communicates to the public the plan for assessing each individual chemical and includes summary information on the IRIS Program’s scoping and initial problem formulation; objectives and specific aims for the assessment; the PECO (Populations, Exposures, Comparators, and Outcomes) criteria that outlines the evidence considered most pertinent to the assessment; and identification of key areas of scientific complexity. The PECO provides the framework for developing literature search strategies and inclusion/exclusion criteria, particularly with respect to evidence stream (i.e., human, animal, mechanistic), exposure and outcome measures. The IAP serves to inform the subsequent development of the chemical specific systematic review protocol.

Background

Vanadium is a transition metal that occurs naturally in Earth’s crust. Fossil fuel combustion is thought to be the major anthropogenic source of vanadium to the atmosphere. The use of heavy oils and bitumen from tar sands and the use of vanadium in industrial applications (e.g., steel production, vanadium redox-flow batteries, and catalytic converters) can contribute to the release of vanadium into the environment.

History/Chronology
Date Description
May 2021 EPA released the IRIS Assessment Plan (IAP) for Inhalation Exposure to Vanadium and Compounds for a 30-day public comment period. [Federal Register Notice May 28, 2021]
Jun 2021 EPA announced an extension of the public comment period until July 13, 2021. [Federal Register Notice Jun 25, 2021]

Status

Following the public (webinar) meeting, the IRIS Program will use the IAP to inform the subsequent development of a chemical-specific systematic review protocol.

Download(s)

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

  • IRIS Assessment Plan for Inhalation Exposure of Vanadium and Compounds (Scoping and Problem Formulation Materials) (PDF)  (64  pp, 1.4 MB, about PDF)

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.

Document Related Link(s)

  • EPA-HQ-ORD-2020-0182
  • Health Effects Assessment for Vanadium and Compounds
  • IRIS Toxicological Review of Vanadium Pentoxide (External Review Draft, 2012)
  • IRIS Assessment Plan for Oral Exposure to Vanadium and Compounds (Scoping and Problem Formulation Materials)

HERO Project

  • Literature Search References Sorted By Author (Vanadium Inhalation)

Federal Register Notices

  • FR Notice: Jun 25, 2021
  • FR Notice: May 28, 2021

Quick Check

Image text: 1. (highlighted) Draft Development, 2. Agency Review, 3. Interagency Science Consultation, 4. Public Comment and External Peer Review, 5. Revise Assessment, 6. Final Agency Review/Interagency Science Discussion, 7. Final Assessment
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Last updated on June 25, 2021
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