Perfluorononanoic Acid (PFNA)
CASRN 375-95-1 | DTXSID8031863
IRIS Toxicological Review of Perfluorononanoic Acid (PFNA) and Related Salts (Interagency Science Consultation Draft, 2023)
Overview
Citation
Background
PFNA has been used to make fluoropolymers, a coating that can resist heat, water, and chemicals; thus, PFNA can be present in products including carpets, food-contact papers, and cleaning and polishing products. Low levels of PFNA are detected in aqueous film-forming foam (AFFF) for fire suppression. PFNA is also a breakdown product of other PFAS (e.g. 8:2 fluorotelomer alcohol).
History/Chronology
Date | Description |
---|---|
Nov 2019 | EPA released the Systematic Review Protocol for the PFAS IRIS Assessment (Preliminary Assessment Materials). [Federal Register Notice Nov 8, 2019] |
Jul 2020 | EPA released an update to the Systematic Review Protocol for the PFBA, PFHxA, PFHxS, PFNA, and PFDA IRIS Assessments in response to public comments. |
Jul 2023 | EPA sent an interagency science consultation PFNA draft for review and comment. |
Mar 2024 | EPA released the draft IRIS Toxicological Review of Perfluorononanoic Acid (PFNA) and Related Salts for a 60-day public comment period and external peer review. The comments on the Interagency Science Consultation Draft were also released. [Federal Register Notice Mar 07, 2024 ] |
Status
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- 1. ATSDR PFNA IASC Comments July 2023 (PDF) (3 pp, 199.2 KB, about PDF)
- 2. DoD PFNA IASC Comments July 2023 (PDF) (30 pp, 373.0 KB, about PDF)
- 3. DOE PFNA IASC Comments July 2023 (PDF) (2 pp, 116.2 KB, about PDF)
- 4. FDA PFNA IASC Comments July 2023 (PDF) (2 pp, 129.9 KB, about PDF)
- 5. NIEHS PFNA IASC Comments July 2023 (PDF) (9 pp, 321.3 KB, about PDF)
- 6. NIOSH PFNA IASC Comments July 2023 (PDF) (1 pp, 140.6 KB, about PDF)
- 7. USDA PFNA IASC Comments July 2023 (PDF) (1 pp, 106.4 KB, about PDF)
- 8. ATSDR PFNA IASC Hepatic Comments December 2023 (PDF) (1 pp, 114.3 KB, about PDF)
- 9. DoD PFNA IASC Appendix Comments December 2023 (PDF) (4 pp, 85.0 KB, about PDF)
- 10. DoD PFNA IASC Hepatic Comments December 2023 (PDF) (3 pp, 85.9 KB, about PDF)
- 11. NIEHS PFNA IASC Hepatic Comments December 2023 (PDF) (1 pp, 148.4 KB, about PDF)
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