IRIS

Benzo[a]pyrene (BaP)

CASRN 50-32-8 | DTXSID2020139

IRIS Toxicological Review of Benzo[a]pyrene (Public Comment Draft)

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Overview

EPA is developing an Integrated Risk Information System (IRIS) assessment of benzo[a]pyrene and has released the draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.

Citation

U.S. EPA. IRIS Toxicological Review of Benzo[a]pyrene (Public Comment Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-13/138a-b, 2013.

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Background

Benzo[a]pyrene is a five-ring polycyclic aromatic hydrocarbon that is relatively insoluble in water and has low volatility. It is ubiquitous in the environment primarily as a result of incomplete combustion emissions. Natural sources of benzo[a]pyrene include forest fires and volcanoes, and anthropogenic sources include stoves/furnaces burning fossil fuels (especially wood and coal), motor vehicle exhaust, and various industrial combustion processes. Major sources of occupational exposure involve production of aluminum, coke, graphite and silicon carbide, as well as coal tar distillation. Major sources of non-occupational exposure involve tobacco products and diet (e.g., barbequed or charred meats).

This public comment draft is a reassessment of an IRIS assessment posted in 1987 and includes an oral reference dose, inhalation reference concentration, oral slope factor, inhalation unit risk, and dermal slope factor. It is the first IRIS assessment to propose a dermal slope factor.

History/Chronology


Status

Following public comment and external peer review, the assessment will be revised taking into consideration peer review and public comments. The assessment will then undergo a final EPA internal review and a review by other federal agencies and the Executive Office of the President. Once final, the assessment will be posted to the IRIS database.

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Download(s)

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

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Docket

Comments on the assessment may be submitted and reviewed using the Docket ID EPA-HQ-ORD-2011-0391

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