Nitrobenzene
CASRN 98-95-3 | DTXSID3020964
- Toxicological Review (PDF) (250 pp, 3.7 MB)
- IRIS Summary (PDF) (30 pp, 251.0 KB)
IRIS Toxicological Review of Nitrobenzene (External Review Draft)
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Overview
Nitrobenzene is used extensively in chemical manufacturing, especially in the synthesis of other industrial chemicals and intermediates. Most important among these is aniline. A re-assessment of the potential health effects of nitrobenzene has been undertaken. The draft assessment will present reference values for the noncancer effects (RfD and RfC) and a cancer assessment (IUR).
Citation
Background
Combined with specific exposure information, government and private entities can use IRIS to help characterize public health risks of chemical substances in a site-specific situation and thereby support risk management decision designed to protect public health.
History/Chronology
Date | Description |
---|---|
Mar 2007 | EPA released the external review draft for public review and comment. |
May 2007 | EPA hosted an independent peer review panel workshop to discuss the draft report. |
Feb 2009 | EPA released the final Toxicological Review of Nitrobenzene: in support of the Integrated Risk Information System (IRIS). |
Status
Additional Information
Download(s)
- Toxicological Review of Nitrobenzene (External Review Draft) (PDF) (169 pp, 2.0 MB, about PDF)
- APPENDIX B -1: DOSE-RESPONSE MODELING FOR DERIVATION OF AN RFD FOR NITROBENZENE (PDF) (62 pp, 407.2 KB, about PDF)
- Charge to External Peer Reviewers (PDF) (4 pp, 31.2 KB, about PDF)
- CONSOLIDATED COMMENTS FROM THE EXTERNAL PEER REVIEW (FINAL) (PDF) (43 pp, 222.7 KB, about PDF)
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