Chloroform

CASRN 67-66-3 | DTXSID1020306

Toxicological Review (PDF) (112 pp, 741.2 KB, about PDF)
IRIS Summary (PDF) (41 pp, 228.5 KB, about PDF)
Status: chloroform is in step 4 at this time.

IRIS Toxicological Review of Chloroform (Final Report, 2001)

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Overview
Background
Downloads

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Overview

EPA is announcing the release of the final report, Toxicological Review of Chloroform: in support of the Integrated Risk Information System (IRIS). The updated Summary for Chloroform and accompanying final report have also been added to the IRIS Database.

Background

Chloroform (trichloromethane) is a colorless, volatile liquid with a distinct odor. Chloroform is nonflammable. It is slightly soluble in water and is readily miscible with most organic solvents. Because chloroform is relatively volatile, it tends to escape from contaminated environmental media (e.g., water or soil) into air, and may also be released in vapor form from some types of industrial or chemical operations. Therefore, humans may be exposed to chloroform not only by ingestion of chloroform in drinking water, food, or soil, but also by dermal contact with contaminated media (especially water) and by inhalation of vapor (especially in indoor air).

History/Chronology
Date	Description
Sep 1984	EPA released the Health Effects Assessment for Chloroform.
Apr 1988	EPA released the Updated Health Effects Assessment for Chloroform.
Oct 2001	EPA released the final tox report and summary document and posted these to the IRIS database.

Download(s)

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

IRIS Toxicological Review and Summary Documents for Chloroform (2001 Final) (PDF) (112 pp, 913.1 KB, about PDF)
IRIS Summary of Chloroform (PDF) (39 pp, 231.4 KB, about PDF)
BMDS Modeling for Chloroform (ZIP) (193.4 KB, about ZIP)

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