IRIS

Pentachlorophenol

CASRN 87-86-5 | DTXSID7021106

IRIS Toxicological Review of Pentachlorophenol (External Review Draft)

On this page:

Notice - This site contains archived material(s)

Archive disclaimer
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the Risk Webmaster for assistance. Please use the contact us form if you need additional support.


Overview

EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of pentachlorophenol that will appear in the Integrated Risk Information System (IRIS) database.

Citation

U.S. EPA. IRIS Toxicological Review of Pentachlorophenol (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-09/004, 2009.

Top of Page


Background

The draft Toxicological Review of Pentachlorophenol provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to pentachlorophenol. Pentachlorophenol is a wood preservative used to prevent decay from fungal organisms and insect damage. Use by the public was restricted in 1984, and application was limited to industrial areas. It has been reported in food, surface water, groundwater, rainwater, and soil. People who work or reside in close proximity to wood treatment facilities, treated lumber, or hazardous waste sites are likely exposed.

This assessment contains a revised oral reference dose (RfD) for chronic noncancer health effects as well as a revised oral cancer risk estimate.

History/Chronology

Date Description
01- Jan 1987 EPA posted the pentachlorophenol assessment on the IRIS database (RfD only).
02- Mar 1991 EPA posted the carcinogenicity assessment for oral exposure to pentachlorophenol on the IRIS database.
03- May 2009 EPA released an updated draft report for public review and comment.
04- Jun 2009 EPA announced a public listening session for the draft review report.
05- Jun 2009 EPA announced a external peer review meeting to be held August 4th in Arlington, VA.
06- Oct 2009 EPA releases the comments from the public comment period and external review workshop.

Status

Following the External Peer Review, the final assessment will be published on the IRIS database.

Additional Information

Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select Environmental Protection Agency and the keyword EPA-HQ-ORD-2009-0178 (for the docket ID) to comment on this report.

Top of Page

Download(s)

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.



Top of Page