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Formaldehyde

CASRN 50-00-0 | DTXSID7020637

  • Toxicological Review (PDF)  (927  pp, 16.3 MB, about PDF)
  • IRIS Executive Summary (PDF)  (10  pp, 450.2 KB, about PDF)
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Statistical Inferences from Formaldehyde Dna-Protein Cross-Link Data

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  • Overview

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Overview

Physiologically-based pharmacokinetic (PBPK) modeling has reached considerable sophistication in its application in the pharmacological and environmental health areas. Yet, mature methodologies for making statistical inferences have not been routinely incorporated in these applications except in a few data-rich cases. In this paper, we work with a previously developed PBPK model for the formation and disposition of DNA-protein cross-links formed by inhaled formaldehyde in the nasal lining of rats and rhesus monkeys and provide improved statistical inference on estimated model parameters. We purposefully choose this model because it is based on sparse time course data.

Related Links

  • EPA Chemicals Dashboard - Formaldehyde
  • EPA Workshop on Formaldehyde (April 2014)
  • IRIS Summary of Formaldehyde (Cancer, 1989)
  • IRIS Summary of Formaldehyde (Noncancer, 1990)
  • Supporting Documents for Formaldehyde
  • eChemPortal - Formaldehyde

Critical Effect Systems

Gastrointestinal
Gastrointestinal

Respiratory
Respiratory

Urinary
Urinary

Tumor Sites

Hematologic
Hematologic

Respiratory
Respiratory

Chemical Structure for
Formaldehyde

Formaldehyde

Synonyms

  • Aldehyd mravenci (Czech)
  • Aldehyde formique (French)
  • Aldeide formica (Italian)
  • BFV
  • FA
  • Formaldehyd (Czech, Polish)
  • Formaldehyde
  • Formaldehyde solution (DOT)
  • Formalin
  • Formalith
  • Formic aldehyde
  • Formol
  • Fyde
  • Hoch
  • Ivalon
  • Karsan
  • Lysoform
  • Methanal
  • Methyl aldehyde
  • Methylene glycol
  • Methylene oxide
  • Morbicid
  • NCI-C02799
  • Oplossingen (Dutch)
  • Oxomethane
  • Oxymethylene
  • Paraform
  • Polyoxymethylene glycols
  • RCRA Waste Number U122
  • Superlysoform
  • UN 1198 (DOT)
  • UN 2209 (DOT)
  • 50-00-0
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Last updated on October 29, 2015
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