Tetrachloroethylene (Perchloroethylene)

Overview

The known toxic effects of perchloroethylene will be summarized, with citations from current scientific literature. The critical effects will be identified, and from this the RfD and RfC and cancer unit risk factors will be derived. The RfD and RfC are reference doses and air concentrations that are generally regarded as safe under conditions of chronic exposure. The cancer unit risks in air and drinking water are the estimated lifetime cancer risks expected to occur from a lifetime exposure to a concentration of 1 microgram per cubic meter in the air and to a drinking water concentration of 1 microgram per liter. This summary document will be peer reviewed within the Agency and by experts outside the Agency according to the standard IRIS procedures. For up-to-date project schedules see IRIS Track at https://cfpub.epa.gov/iristrac/index.cfm

Document Related Link(s)

• Charge to the Tetrachloroethylene (Perchloroethylene) Neurotoxicity Expert Panel
• IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (External Review Draft)