Polychlorinated Biphenyls (PCBs)

Overview

In December 2019, EPA released the Systematic Review Protocol for the Polychlorinated Biphenyls (PCBs) Noncancer IRIS Assessment (Preliminary Assessment Materials). As part of developing a draft IRIS assessment, EPA presents a methods document, referred to as the protocol, for conducting a chemical-specific systematic review of the available scientific literature. Protocols include strategies for literature searches, criteria for study inclusion or exclusion, considerations for evaluating study methods, information management for extracting data, approaches for synthesis within and across lines of evidence, and methods for derivation of toxicity values.

History/Chronology

Date	Description
Mar 2015	EPA released the IRIS Toxicological Review Of Polychlorinated Biphenyls (PCBs) (Scoping And Problem Formulation Materials) for public comment.
Jun 2015	On June 17-18, 2015, EPA hosted an IRIS public science meeting to provide an opportunity for the public to give input and participate in an open discussion regarding scoping and problem formulation materials that were prepared for the IRIS assessment, Polychlorinated Biphenyls (PCBs): Effects Other Than Cancer, prior to the development of the draft assessment.
Dec 2019	EPA released the Systematic Review Protocol For The Polychlorinated Biphenyls (PCBs) Noncancer IRIS Assessment (Preliminary Assessment Materials) (Report) for public review and comment. [Federal Register Notice Dec 19, 2019]

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

• Systematic Review Protocol for the Polychlorinated Biphenyls Noncancer IRIS Assessment (Preliminary Assessment Materials) (PDF)  (143  pp, 3.6 MB, about PDF)

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Document Related Link(s)

• IRIS Toxicological Review of Polychlorinated Biphenyls (PCBs) (Scoping and Problem Formulation Materials)

Federal Register Notices

• FR Notice: Dec 19, 2019

Docket

Comments on the assessment may be submitted and reviewed using the Docket ID EPA-HQ-ORD-2011-0676