IRIS

Perfluorodecanoic Acid (PFDA)

CASRN 335-76-2 | DTXSID3031860

IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) (Peer Review Draft)

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Overview

EPA will be developing an Integrated Risk Information System (IRIS) assessment of Perfluorodecanoic Acid (PFDA) with an external review draft assessment for public comment and external peer review. When final, the assessment will appear on the IRIS database.

Citation

U.S. EPA. IRIS Toxicological Review of Perfluorodecanoic Acid (PFDA) (Peer Review Draft). U.S. Environmental Protection Agency, Washington, DC.

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Background

Perfluorodecanoic Acid (PFDA, CASRN 375-22 -4) is a member of the group per and polyfluoroalkyl substances (PFAS). Concerns about PFDA and other PFAS stem from the resistance of these compounds to hydrolysis, photolysis, and biodegradation, which leads to their persistence in the environment. PFASs are not naturally occurring in the environment; they are man-made compounds that have been used widely over the past several decades in consumer products and industrial applications because of their resistance to heat, oil, stains, grease, and water. PFDA is a breakdown product of other PFASs that are used in stain-resistant fabrics, paper food packaging, and carpets; it was also used for manufacturing photographic film, and it is used as a substitute for longer chain perfluorocarboxylic acids (PFCAs) in consumer products. PFDA has been found to accumulate in agricultural crops and it has been detected in household dust, soils, food products, and surface, ground, and drinking water. As such, exposure is possible via inhalation of indoor or outdoor air, ingestion of drinking water and food, and dermal contact with PFDA-containing products.

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Download(s)

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

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