Chromium(VI)
CASRN 18540-29-9 | DTXSID7023982
- Toxicological Review (PDF) (538 pp, 9.6 MB)
- IRIS Summary (PDF) (14 pp, 461.9 KB)
IRIS Toxicological Review of Hexavalent Chromium (Interagency Science Consultation Draft, 2022)
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Overview
Citation
Background
History/Chronology
| Date | Description |
|---|---|
| Apr 2014 | EPA released preliminary meeting materials for chromium (VI), part 1, in preparation for the June 2014 Bimonthly Public Science Meeting. |
| Jun 2014 | EPA hosted a public science meeting to discuss preliminary meeting materials for chromium (VI), part 1. |
| Aug 2014 | EPA released preliminary meeting materials for chromium (VI), part 2, in preparation for the October 2014 Bimonthly Public Science Meeting. |
| Oct 2014 | EPA hosted a public science meeting to discuss preliminary meeting materials for chromium (VI), part 2. |
| Mar 2019 | EPA released the Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials). [Federal Register Notice Mar 15, 2019] |
| Apr 2019 | EPA announced that they will host a public science meeting on April 24, 2019 (by webinar) to discuss the draft document. |
| Feb 2022 | EPA initiated an interagency science consultation to review the draft toxicological review and charge to external peer reviewers. |
| Oct 2022 | EPA released the EPA-led Interagency Science Consultation draft (Feb 2022) report with interagency comments on the EPA website. |
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- IRIS Toxicological Review of Hexavalent Chromium (Interagency Science Consultation Draft) (PDF) (504 pp, 8.8 MB, about PDF)
- IRIS Toxicological Review of Hexavalent Chromium - Supplemental Information (Interagency Science Consultation Draft) (PDF) (432 pp, 12.5 MB, about PDF)
- Charge to the External Reviewers (PDF) (7 pp, 229.5 KB, about PDF)
- 1. ATSDR CrVI IASC Comments Feb2022 (PDF) (6 pp, 167.0 KB, about PDF)
- 2. DoD CrVI IASC Comments Feb2022 (PDF) (5 pp, 167.0 KB, about PDF)
- 3. EOP CrVI IASC Comments Feb2022 (PDF) (4 pp, 123.0 KB, about PDF)
- 4. NIEHS CrVI IASC Comments Feb2022 (PDF) (10 pp, 190.4 KB, about PDF)
- 5. NIOSH CrVI IASC Comments Feb2022 (PDF) (2 pp, 177.7 KB, about PDF)
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Document Related Link(s)
- IRIS Toxicological Review of Hexavalent Chromium Part 1: Experimental Animal Studies (Preliminary Assessment Materials, 2014)
- IRIS Toxicological Review of Hexavalent Chromium Part 2: Human, Toxicokinetic, and Mechanistic Studies (Preliminary Assessment Materials, 2014)
- Updated Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials, 2019)
- IRIS Toxicological Review of Hexavalent Chromium (External Review Draft, 2022)
Critical Effect Systems
Tumor Sites
Chemical Structure for
Chromium(VI)
