Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

  • Environmental Topics
  • Laws & Regulations
  • Report a Violation
  • About EPA
IRIS
Contact Us

Chloroform

CASRN 67-66-3 | DTXSID1020306

  • Toxicological Review (PDF)  (112  pp, 741.2 KB, about PDF)
  • IRIS Summary (PDF)  (41  pp, 228.5 KB, about PDF)
  • Status: chloroform is in step 4 at this time.
  • Key IRIS
    Values
  • Assessment
    Status
  • Chemical
    Documents
  • Report
    Details
  • Other EPA
    Information

Health Effects Assessment for Chloroform

On this page:

  • Overview
  • Background
  • Downloads

Alert
Alert Notice - This site contains archived material(s)

Archive disclaimer
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the IRIS Webmaster for assistance. Please use the contact us form if you need additional support.

Overview

The document represents a brief, quantitatively oriented scientific summary of health effects data. It was developed by the Environmental Criteria and Assessment Office to assist the Office of Emergency and Remedial Response in establishing chemical-specific health-related goals of remedial actions. If applicable, chemical-specific subchronic and chronic toxicity interim acceptable intakes are determined for systemic toxicants, or q(sub 1)* values are determined for carcinogens for both oral and inhalation routes. A q(sub 1)* was determined for chloroform base on oral exposure.


Additional Information

See also PB84-195163, PB86-134202 and PB86-134228. repared in cooperation with Syracuse Research Corp., NY.

Download(s)

  • HEALTH EFFECTS ASSESSMENT FOR CHLOROFORM

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.

Quick Check

Image text: 1. Draft Development, 2. Agency Review, 3. Interagency Science Consultation, 4. (highlighted) Public Comment and External Peer Review, 5. Revise Assessment, 6. Final Agency Review/Interagency Science Discussion, 7. Final Assessment

Related Links

  • EPA Chemicals Dashboard - Chloroform
  • eChemPortal - Chloroform

Critical Effect Systems

Hepatic
Hepatic

Tumor Sites

Hepatic
Hepatic

Chemical Structure for
Chloroform

Chloroform

Synonyms

  • Chloroform
  • Formyl trichloride
  • Freon 20
  • Methane trichloride
  • Methane, trichloro-
  • Methenyl chloride
  • Methenyl trichloride
  • Methyl trichloride
  • NCI-C02686
  • R-20
  • TCM
  • Trichloroform
  • Trichloromethane
  • 67-66-3
  • IRIS Home
  • About IRIS
  • IRIS Recent Additions
  • IRIS Calendar
  • IRIS Assessments
  • Advanced Search
  • IRIS Program Materials
Contact Us to ask a question, provide feedback, or report a problem.
Last updated on January 16, 2018
United States Environmental Protection Agency

Discover.

  • Accessibility Statement
  • Budget & Performance
  • Contracting
  • EPA www Web Snapshots
  • Grants
  • No FEAR Act Data
  • Privacy
  • Privacy and Security Notice

Connect.

  • Data.gov
  • Inspector General
  • Jobs
  • Newsroom
  • Open Government
  • Regulations.gov
  • Subscribe
  • USA.gov
  • White House

Ask.

  • Contact EPA
  • EPA Disclaimers
  • Hotlines
  • FOIA Requests
  • Frequent Questions

Follow.