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Chloroform

CASRN 67-66-3 | DTXSID1020306

  • Toxicological Review (PDF)  (112  pp, 741.2 KB, about PDF)
  • IRIS Summary (PDF)  (41  pp, 228.5 KB, about PDF)
  • Status: chloroform is in step 4 at this time.
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Updated Health Effects Assessment for Chloroform

On this page:

  • Overview
  • Background
  • Downloads

Alert
Alert Notice - This site contains archived material(s)

Archive disclaimer
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the IRIS Webmaster for assistance. Please use the contact us form if you need additional support.

Overview

This report summarizes and evaluates infornation relevant to a preliminary interim assessment of adverse health effects associated with specific chemicals or compounds. The Office of Emergency and Remedial Response (Superfund) uses these documents in preparing cost-benefit analyses under Executive Order 12991 for decision-making under CERCLA. All estimates of acceptable intakes and carcinogenic potency presented in this document should be considered as preliminary and reflect limited resources allocated to this project. The intent in these assessments is to suggest acceptable exposure levels whenever sufficient data are available. he interim values presented reflect the relative degree of hazard associated with exposure or risk to the chemical(s) addressed. Whenever possible, two categories of values have been estimated for systemic toxicants (toxicants for which cancer is not the endpoint of concern). The first, RfDS or subchronic reference dose, is an estimate of an exposure level that would not be expected to cause adverse effects when exposure occurs during a limited time interval. The RfD is an estimate of an exposure level that would not be expected to cause adverse effects when exposure occurs for a significant portion of the lifespan. For compounds for which there is sufficient evidence of carcinogenicity, ql*s have been computed, if appropriate, based on oral and inhalation data if available.


Additional Information

Project Officer Chris DeRosa, FTS 684-7534

Download(s)

  • UPDATED HEALTH EFFECTS ASSESSMENT FOR CHLOROFORM

If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact Us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.

Quick Check

Image text: 1. Draft Development, 2. Agency Review, 3. Interagency Science Consultation, 4. (highlighted) Public Comment and External Peer Review, 5. Revise Assessment, 6. Final Agency Review/Interagency Science Discussion, 7. Final Assessment

Related Links

  • EPA Chemicals Dashboard - Chloroform
  • eChemPortal - Chloroform

Critical Effect Systems

Hepatic
Hepatic

Tumor Sites

Hepatic
Hepatic

Chemical Structure for
Chloroform

Chloroform

Synonyms

  • Chloroform
  • Formyl trichloride
  • Freon 20
  • Methane trichloride
  • Methane, trichloro-
  • Methenyl chloride
  • Methenyl trichloride
  • Methyl trichloride
  • NCI-C02686
  • R-20
  • TCM
  • Trichloroform
  • Trichloromethane
  • 67-66-3
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Last updated on January 16, 2018
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