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Pentachlorophenol

CASRN 87-86-5 | DTXSID7021106

  • Toxicological Review (PDF)  (288  pp, 2.1 MB, about PDF)
  • IRIS Summary (PDF)  (27  pp, 254.9 KB, about PDF)
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PENTACHLOROPHENOL: HEALTH AND ENVIRONMENTAL EFFECTS PROFILE

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Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the IRIS Webmaster for assistance. Please use the contact us form if you need additional support.

Overview

Pentachlorophenol is used as an industrial wood preservative for utility poles, crossarms, fence posts, and other purposes(79%); for NaPCP (12%); and miscellaneous including mill uses, consumer wood preserving formulations and herbicide intermediate (9%). hotolysis and microbial degradation are the important chemical removal mechanisms for pentachlorophenol (PCP) in water. irect photolysis may be an important environmental sink for PCP present in the atmosphere. oil degradation studies indicate the PCP is biodegradable; microbial decomposition is an important and potentially dominant removal mechanism in soil. onitoring studies have confirmed the widespread occurrence of PCP in surface waters, groundwater, drinking water and industrial effluents. cute toxicity data indicated that salmonids are more sensitive to the toxic effects of PCP than other fish species. PCP is readily absorbed from the gastrointestinal tract of rats, mice, monkeys and humans. he primary route of excretion after oral administration of all species studied is in the urine. eratogenicity/reproductive studies indicate PCP is fetotoxic in rats. Subchronic and chronic toxicity studies show adverse effects in the liver, kidney and immune system. n ADI of 0.03 mg/kg/day or 2.1 mg/day for a 70 kg human was derived from a chronic dietary study in rats. n RQ of 100 was derived based on fetotoxic effects in rats. nadequate evidence exists for carcinogenicity.


Additional Information

Toxicology and Industrial Health, 2(4):483-571, 1986

Download(s)

  • PENTACHLOROPHENOL: HEALTH AND ENVIRONMENTAL EFFECTS PROFILE

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Related Links

  • EPA Chemicals Dashboard - Pentachlorophenol
  • eChemPortal - Pentachlorophenol

Critical Effect Systems

Hepatic
Hepatic

Tumor Sites

Endocrine
Endocrine

Hepatic
Hepatic

Chemical Structure for
Pentachlorophenol

Pentachlorophenol

Synonyms

  • Chem-Tol
  • Chlorophen
  • Cryptogil OL
  • DP-2, technical
  • Dowcide 7
  • Dowicide EC-7
  • Durotox
  • EP 30
  • Fungifen
  • Glazd penta
  • Grundier arbezol
  • Lauxtol
  • Lauxtol A
  • Liroprem
  • NCI-C54933
  • NCI-C55378
  • NCI-C55389
  • NCI-C56655
  • PCP
  • Penchlorol
  • Penta
  • Penta-Kil
  • Pentachloorfenol
  • Pentachlorofenol
  • Pentachlorofenolo
  • Pentachlorophenate
  • Pentachlorophenol
  • Pentachlorphenol
  • Pentaclorofenolo
  • Pentacon
  • Pentasol
  • Penwar
  • Peratox
  • Permacide
  • Permagard
  • Permasan
  • Permatox
  • Permatox dp-2
  • Permatox penta
  • Permite
  • Phenol, pentachloro-
  • Preventol P
  • Priltox
  • Santobrite
  • Santophen
  • Santophen 20
  • Sinituho
  • Term-i-trol
  • WLN: QR BG CG DG EG FG
  • 1-Hydroxy- 2,3,4,5,6-pentachlorobenzene
  • 2,3,4,5,6-Pentachlorophenol
  • 87-86-5
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Last updated on July 22, 2004
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