1,2,3-Trichloropropane

Overview

EPA's assessment of the noncancer health effects and carcinogenic potential of 1,2,3-trichloropropane (TCP) was added to the IRIS database in 1990. The IRIS program is updating the IRIS assessment for TCP. This update will incorporate health effects information published since the last assessment was prepared as well as new risk assessment methods. The IRIS assessment for TCP will consist of a Toxicological Review and IRIS Summary. The Toxicological Review is a critical review of the physicochemical and toxicokinetic properties of the chemical and its toxicity in humans and experimental systems. The assessment will present reference values for noncancer effects of TCP (RfD and RfC) and a cancer assessment. The Toxicological Review and IRIS Summary will be subject to internal peer consultation, Agency review, and external scientific peer review. The final products will constitute the Agency's opinion on the toxicity of TCP.

• Link to Peer Review Charge and Report 123 Trichloropropane (PDF)  (NA  pp, 3.9 KB, about PDF)

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Document Related Link(s)

• IRIS Toxicological Review of 1,2,3-Trichloropropane (External Review Draft)
• IRIS Toxicological Review of 1,2,3-trichloropropane (Interagency Science Discussion Draft)