Methods For Derivation Of Inhalation Reference Concentrations (RfCs) And Application Of Inhalation Dosimetry
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Overview
The overview chapter discusses general prinicples of dose-response assessment for noncancer assessment process. Subsequent chapters of the document discuss criteria and information to be considered in selecting key studies for RfC derivation, provide an overview of the respiratory system and its intra- and interspecies variables, and discuss areas of uncertainty and data gaps in relation to the proposed methodology.
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- Methods for Derivation (Full Report) (PDF) (409 pp, 19.6 MB, about PDF)
- Methods for Derivation part 1 (PDF) (100 pp, 5.3 MB, about PDF)
- Methods for Derivation part 2 (PDF) (100 pp, 5.5 MB, about PDF)
- Methods for Derivation part 3 (PDF) (100 pp, 5.8 MB, about PDF)
- Methods for Derivation part 4 (PDF) (109 pp, 4.7 MB, about PDF)
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