IRIS Home | Critical Effect Search Results

Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the RfD, RfC, oral slope factor, or inhalation unit risk. Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with organ/system filters. IRIS Advanced Search searches only final IRIS assessments; to look for information on draft assessments, see Quick Check: Assessments in Development.

Search Filtered by: Critical Effect = "Dermal"
Number of records: 8
Chemical Name CASRN Exposure Route Critical Effect RfD/RfC RfD/RfC Value
Aroclor 1254 11097-69-1 Oral Ocular exudate, inflamed and prominent Meibomian glands, distorted growth of finger and toe nails; decreased antibody (IgG and IgM) response to sheep erythrocytes RFD 2 x 10 -5 mg/kg-day
Arsenic, Inorganic 7440-38-2 Oral Hyperpigmentation, keratosis and possible vascular complications RFD 3 x 10 -4 mg/kg-day
Fluvalinate 69409-94-5 Oral Decreases in body weight gain increase in plantar ulcer (females) RFD 1 x 10 -2 mg/kg-day
Selenious acid 7783-00-8 Oral Clinical selenosis RFD 5 x 10 -3 mg/kg-day
Selenium and Compounds 7782-49-2 Oral Clinical selenosis RFD 5 x 10 -3 mg/kg-day
Silver 7440-22-4 Oral Argyria RFD 5 x 10 -3 mg/kg-day
Vanadium pentoxide 1314-62-1 Oral Decreased hair cystine RFD 9 x 10 -3 mg/kg-day
White phosphorus 7723-14-0 Oral Parturition mortality; forelimb hair loss RFD 2 x 10 -5 mg/kg-day