IRIS Critical Effect Search Results

Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the RfD, RfC, oral slope factor, or inhalation unit risk. Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with organ/system filters. IRIS Advanced Search searches only final IRIS assessments; to look for information on draft assessments, see Quick Check: Assessments in Development.

Search Filtered by: Critical Effect = "Dermal"
Number of records: 7

Chemical Name	CASRN	Exposure Route	Critical Effect	RfD/RfC	RfD/RfC Value
Aroclor 1254	11097-69-1	Oral	Ocular exudate, inflamed and prominent Meibomian glands, distorted growth of finger and toe nails; decreased antibody (IgG and IgM) response to sheep erythrocytes	RFD	2 x 10 ^-5 mg/kg-day
Fluvalinate	69409-94-5	Oral	Decreases in body weight gain increase in plantar ulcer (females)	RFD	1 x 10 ^-2 mg/kg-day
Selenious acid	7783-00-8	Oral	Clinical selenosis	RFD	5 x 10 ^-3 mg/kg-day
Selenium and Compounds	7782-49-2	Oral	Clinical selenosis	RFD	5 x 10 ^-3 mg/kg-day
Silver	7440-22-4	Oral	Argyria	RFD	5 x 10 ^-3 mg/kg-day
Vanadium pentoxide	1314-62-1	Oral	Decreased hair cystine	RFD	9 x 10 ^-3 mg/kg-day
White phosphorus	7723-14-0	Oral	Parturition mortality; forelimb hair loss	RFD	2 x 10 ^-5 mg/kg-day