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Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the
RfD, RfC, oral slope factor, or inhalation unit risk.
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Search Filtered by: Critical Effect = "Ocular"
Number of records: 9
| Chemical Name | CASRN | Exposure Route | Critical Effect | RfD/RfC | RfD/RfC Value |
|---|---|---|---|---|---|
| Aroclor 1254 | 11097-69-1 | Oral | Ocular exudate, inflamed and prominent Meibomian glands, distorted growth of finger and toe nails; decreased antibody (IgG and IgM) response to sheep erythrocytes | RFD | 2 x 10 -5 mg/kg-day |
| Dacthal | 1861-32-1 | Oral | Effects on the lungs, liver, kidney, thyroid and thyroid hormones in males and females and eyes of females | RFD | 1 x 10 -2 mg/kg-day |
| 4,6-Dinitro-o-cyclohexyl phenol | 131-89-5 | Oral | Cataract formation | RFD | 2 x 10 -3 mg/kg-day |
| 2,4-Dinitrophenol | 51-28-5 | Oral | Cataract formation | RFD | 2 x 10 -3 mg/kg-day |
| Diquat | 2764-72-9 | Oral | Minimal lens opacity and cataracts | RFD | 2.2 x 10 -3 mg/kg-day |
| Fluridone | 59756-60-4 | Oral | Glomerulonephritis, atrophic testes, eye keratitis decreased body weight and organ weights | RFD | 8 x 10 -2 mg/kg-day |
| Methyl tert-butyl ether (MTBE) | 1634-04-4 | Inhalation | Increased absolute and relative liver and kidney weights and increased severity of spontaneous renal lesions (females), increased prostration (females), and swollen periocular tissue (males and females) | RFC | 3 mg/m3 |
| Tetrachloroethylene (Perchloroethylene) | 127-18-4 | Oral | (See Note) | RFD | 6 x 10 -3 mg/kg-day |
| Tetrachloroethylene (Perchloroethylene) | 127-18-4 | Inhalation | (See Note) | RFC | 4 x 10 -2 mg/m3 |