IRIS
IRIS Home | Tumor Site Search Results
Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the
RfD, RfC, oral slope factor, or inhalation unit risk.
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Search Filtered by: Tumor Site = "Reproductive"
Number of records: 12
| Chemical Name | CASRN | Exposure Route | WOE Characterization | Tumor Type | Toxicity Value |
|---|---|---|---|---|---|
| Acrylamide | 79-06-1 | Oral |
Likely to be carcinogenic to humans (2005 guidelines) |
thyroid tumors and tunica vaginalis mesotheliomas | |
| Acrylamide | 79-06-1 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
thyroid tumors and tunica vaginalis mesotheliomas | 1 x 10 -4 per µg/m3 |
| Bromate | 15541-45-4 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) Carcinogenic potential cannot be determined (1996 guidelines) Known/likely human carcinogen (1996 guidelines) |
Testicular mesothelioma, renal tubular adenoma and carcinoma, and thyroid follicular cell adenoma and carcinoma | 2 x 10 -5 per µg/L |
| Chloroprene | 126-99-8 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
alveolar/ bronchiolar adenoma or carcinoma hemangioma/ hemangiosarcoma (all organs) mammary gland adenocarcinoma, carcinoma, or adenoacanthoma forestomach squamous cell papilloma or carcinoma hepatocellular adenoma or carcinoma Harderian gland adenoma or carcinoma skin sarcoma and Zymbal's gland carcinoma | 3 x 10 -4 per µg/m3 |
| 1,2-Dibromoethane | 106-93-4 | Inhalation |
Likely to be carcinogenic to humans (1999 guidelines) |
Nasal cavity (includes adenoma, adenocarcinoma, papillary adenoma, squamous cell carcinoma, and or/papilloma), hemangiosarcomas, mesotheliomas |
6 x 10 -4 per µg/m3 95% upper bound |
| 1,2-Dibromoethane | 106-93-4 | Inhalation |
Likely to be carcinogenic to humans (1999 guidelines) |
Nasal cavity (includes adenoma, adenocarcinoma, papillary adenoma, squamous cell carcinoma, and or/papilloma), hemangiosarcomas, mesotheliomas |
3 x 10 -4 per µg/m3 central tendency estimate |
| 3,3'-Dichlorobenzidine | 91-94-1 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) |
Mammary adenocarcinoma | 1.3 x 10 -5 per µg/L |
| 2,4-/2,6-Dinitrotoluene mixture | Various | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) |
Liver: hepatocellular carcinomas, neoplastic nodules; mammary gland: adenomas, fibroadenomas, fibromas, adenocarcinomas/ carcinomas | 1.9 x 10 -5 per µg/L |
| 1,4-Dioxane | 123-91-1 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
Multiple (nasal, liver, kidney, peritoneal, mammary gland, and Zymbal gland) | 5 x 10 -6 per µg/m3 |
| Ethylene oxide | 75-21-8 | Inhalation |
Carcinogenic to humans (2005 guidelines) |
Lymphoid cancer, (female) breast cancer | 3 x 10 -3 per µg/m3 |
| Isophorone | 78-59-1 | Oral |
C (Possible human carcinogen) (1986 guidelines) |
Preputial gland carcinoma | 2.7 x 10 -8 per µg/L |
| 1,2,3-Trichloropropane | 96-18-4 | Oral |
Likely to be carcinogenic to humans (2005 guidelines) |
alimentary system squamous cell neoplasms, liver hepatocellular adenomas or carcinomas, Harderian gland adenomas, uterine/cervix adenomas or carcinomas |