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IRIS Home | Critical Effect Search Results
Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the
RfD, RfC, oral slope factor, or inhalation unit risk.
Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with
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Quick Check: Assessments in Development.
Search Filtered by: Critical Effect = "Gastrointestinal"
Number of records: 12
| Chemical Name | CASRN | Exposure Route | Critical Effect | RfD/RfC | RfD/RfC Value |
|---|---|---|---|---|---|
| Benzaldehyde | 100-52-7 | Oral | Forestomach lesions, kidney toxicity | RFD | 1 x 10 -1 mg/kg-day |
| Beryllium and compounds | 7440-41-7 | Oral | Small intestinal lesions | RFD | 2 x 10 -3 mg/kg-day |
| Bromomethane | 74-83-9 | Oral | Epithelial hyperplasia of the forestomach | RFD | 1.4 x 10 -3 mg/kg-day |
| Chloral hydrate | 302-17-0 | Oral | CNS depression and GI irritation in humans | RFD | 1 x 10 -1 mg/kg-day |
| Cypermethrin | 52315-07-8 | Oral | G.I. tract disturbances | RFD | 1 x 10 -2 mg/kg-day |
| 1,3-Dichloropropene | 542-75-6 | Oral | Chronic irritation | RFD | 3 x 10 -2 mg/kg-day |
| Endothall | 145-73-3 | Oral | Increased absolute and relative weights of stomach and small intestine | RFD | 2 x 10 -2 mg/kg-day |
| Fluorine (soluble fluoride) | 7782-41-4 | Oral | Objectionable dental fluorosis, a cosmetic effect | RFD | 6 x 10 -2 mg/kg-day |
| Formaldehyde | 50-00-0 | Oral | Reduced weight gain, histopathology in rats | RFD | 2 x 10 -1 mg/kg-day |
| Hexachlorocyclopentadiene (HCCPD) | 77-47-4 | Oral | Chronic irritation | RFD | 6 x 10 -3 mg/kg-day |
| Hexachlorophene | 70-30-4 | Oral | Swollen salivary glands, status spongiosis in brain and optic nerve | RFD | 3 x 10 -4 mg/kg-day |
| Propiconazole | 60207-90-1 | Oral | Gastric mucosal irritation | RFD | 1.3 x 10 -2 mg/kg-day |