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Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the RfD, RfC, oral slope factor, or inhalation unit risk. Other effects associated with chemicals in the IRIS database that were not used as the basis for a toxicity value are not searchable with organ/system filters. IRIS Advanced Search searches only final IRIS assessments; to look for information on draft assessments, see Quick Check: Assessments in Development.

Search Filtered by: Tumor Site = "Gastrointestinal"
Number of records: 15
Chemical Name CASRN Exposure Route WOE Characterization Tumor Type Toxicity Value
Acrylonitrile 107-13-1 Oral B1 (Probable human carcinogen - based on limited evidence of carcinogenicity in humans) (1986 guidelines)
Brain and spinal cord astrocytomas, Zymbal gland carcinomas and stomach papillomas/ carcinomas 1.5 x 10 -5 per µg/L
Benzo[a]pyrene (BaP) 50-32-8 Inhalation Carcinogenic to humans (2005 guidelines)
Squamous cell neoplasia in the larynx, pharynx, trachea, nasal cavity, esophagus, and forestomach. 6 x 10 -4 per µg/m3
Benzo[a]pyrene (BaP) 50-32-8 Oral Carcinogenic to humans (2005 guidelines)
forestomach, esophagus, tongue, and larynx tumors
Bromoform 75-25-2 Inhalation B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Neoplastic lesions in the large intestine 1.1 x 10 -6 per µg/m3
Bromoform 75-25-2 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Neoplastic lesions in the large intestine 2.3 x 10 -7 per µg/L
Chloroprene 126-99-8 Inhalation Likely to be carcinogenic to humans (2005 guidelines)
alveolar/ bronchiolar adenoma or carcinoma hemangioma/ hemangiosarcoma (all organs) mammary gland adenocarcinoma, carcinoma, or adenoacanthoma forestomach squamous cell papilloma or carcinoma hepatocellular adenoma or carcinoma Harderian gland adenoma or carcinoma skin sarcoma and Zymbal's gland carcinoma 3 x 10 -4 per µg/m3
1,2-Dibromoethane 106-93-4 Oral Likely to be carcinogenic to humans (1999 guidelines)
Forestomach tumors, hemangiosarcomas, thyroid follicular cell adenomas or carcinomas
1,2-Dibromoethane 106-93-4 Oral Likely to be carcinogenic to humans (1999 guidelines)
Forestomach tumors, hemangiosarcomas, thyroid follicular cell adenomas or carcinomas 6 x 10 -5 per µg/L
95% upper bound
Dichlorvos 62-73-7 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Forestomach tumors, pancreatic acinar adenoma, leukemia 8.3 x 10 -6 per µg/L
1,4-Dioxane 123-91-1 Inhalation Likely to be carcinogenic to humans (2005 guidelines)
Multiple (nasal, liver, kidney, peritoneal, mammary gland, and Zymbal gland) 5 x 10 -6 per µg/m3
Epichlorohydrin 106-89-8 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Papillomas and carcinomas of the forestomach 2.8 x 10 -7 per µg/L
N-Nitroso-di-n-butylamine 924-16-3 Inhalation B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Bladder and esophagus tumors 1.6 x 10 -3 per µg/m3
N-Nitroso-di-n-butylamine 924-16-3 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Bladder and esophagus tumors 1.6 x 10 -4 per µg/L
Propylene oxide 75-56-9 Oral B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines)
Forestomach, squamous cell carcinoma 6.8 x 10 -6 per µg/L
1,2,3-Trichloropropane 96-18-4 Oral Likely to be carcinogenic to humans (2005 guidelines)
alimentary system squamous cell neoplasms, liver hepatocellular adenomas or carcinomas, Harderian gland adenomas, uterine/cervix adenomas or carcinomas