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Searches using filters for organ/system affected are limited to effects (or tumor sites) used to derive the
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Search Filtered by: Tumor Site = "Endocrine"
Number of records: 13
| Chemical Name | CASRN | Exposure Route | WOE Characterization | Tumor Type | Toxicity Value |
|---|---|---|---|---|---|
| Acrylamide | 79-06-1 | Oral |
Likely to be carcinogenic to humans (2005 guidelines) |
thyroid tumors and tunica vaginalis mesotheliomas | |
| Acrylamide | 79-06-1 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
thyroid tumors and tunica vaginalis mesotheliomas | 1 x 10 -4 per µg/m3 |
| Benzyl chloride | 100-44-7 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) |
Thyroid, C-cell adenoma/ carcinoma | 4.9 x 10 -6 per µg/L |
| Bromate | 15541-45-4 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) Carcinogenic potential cannot be determined (1996 guidelines) Known/likely human carcinogen (1996 guidelines) |
Testicular mesothelioma, renal tubular adenoma and carcinoma, and thyroid follicular cell adenoma and carcinoma | 2 x 10 -5 per µg/L |
| Carbon tetrachloride | 56-23-5 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
Pheochromocytoma | 6 x 10 -6 per µg/m3 |
| 1,2-Dibromoethane | 106-93-4 | Oral |
Likely to be carcinogenic to humans (1999 guidelines) |
Forestomach tumors, hemangiosarcomas, thyroid follicular cell adenomas or carcinomas |
6 x 10 -5 per µg/L 95% upper bound |
| 1,2-Dibromoethane | 106-93-4 | Oral |
Likely to be carcinogenic to humans (1999 guidelines) |
Forestomach tumors, hemangiosarcomas, thyroid follicular cell adenomas or carcinomas | |
| Dichlorvos | 62-73-7 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) |
Forestomach tumors, pancreatic acinar adenoma, leukemia | 8.3 x 10 -6 per µg/L |
| 4,4'-Methylene bis(N,N'-dimethyl)aniline | 101-61-1 | Oral |
B2 (Probable human carcinogen - based on sufficient evidence of carcinogenicity in animals) (1986 guidelines) |
Thyroid, follicular cell carcinoma/ adenoma | 1.3 x 10 -6 per µg/L |
| Nitrobenzene | 98-95-3 | Inhalation |
Likely to be carcinogenic to humans (2005 guidelines) |
Liver hepatocellular adenomas or carcinomas, kidney tubular adenomas or carcinomas, thyroid follicular cell adenomas or carcinomas | 4 x 10 -5 per µg/m3 |
| Pentachlorophenol | 87-86-5 | Oral |
Likely to be carcinogenic to humans (2005 guidelines) |
Hepatocellular adenomas or carcinomas and adrenal benign or malignant pheochromocytomas | 1.1 x 10 -5 per µg/L |
| Trifluralin | 1582-09-8 | Oral |
C (Possible human carcinogen) (1986 guidelines) |
Combined renal pelvis carcinomas, urinary bladder papillomas and/or thyroid adenomas and carcinomas | 2.2 x 10 -7 per µg/L |
| tert-Butyl Alcohol (tBA) | 75-65-0 | Oral |
Suggestive evidence of carcinogenic potential (2005 guidelines) |
Renal adenomas and carcinomas, thyroid adenomas |